Protein Alignment tld and Pcolce2

DIOPT Version :9

• Sequence 1: NP_524487.2
• Gene: tld / 42945
• FlyBaseID: FBgn0003719
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_083896.1
• Gene: Pcolce2 / 76477
• MGIID: 1923727
• Length: 414
• Species: Mus musculus
• Alignment Length: 330
• Identity: 99/330 - (30%)
• Similarity: 154/330 - (46%)
• Gaps: 64/330 - (19%)

  Fly   478 CGGDLKLTKDQS-IDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDFVEIRD 541
            |||  .||.:.. |.|..:|..|.|:.:|.|:||.|:...|.|.|:..:||..:.|.||||::.:
Mouse    32 CGG--ILTGESGFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFIDLENDNLCRYDFVDVYN 94

  Fly   542 GNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHGCQHLC 606
            | |::.:.||||||...|.::....|:|.::.:||:
Mouse    95 G-HANGQRIGRFCGTFRPGSLVASGNKMTVQMISDA----------------------------- 129

  Fly   607 INTLGSYQCGCRAGYELQANGKTCEDACGGVVDATKSNGSLYSPSYPD-VYPNSKQCVWEVVAPP 670
             ||.||   |..|.|...|.....:..|||.::  |.:|:..:|::|| .||....|||.::||.
Mouse   130 -NTAGS---GFMATYSAAAPDGKGDRYCGGRLE--KPSGTFKTPNWPDRDYPVGVTCVWHIIAPK 188

  Fly   671 NHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQSILRLEF 735
            |..:.|.|..||:|  |.:|  |.|||:.:::....|..|:||.|||...|..:.||::.|.::|
Mouse   189 NQLIELKFEKFDVE--RDNY--CRYDYVAVFNGGEVNDAKRIGKYCGDSPPVPIVSERNELLIQF 249

  Fly   736 YSDRTVQRSGFVAKF-----------VIDVDECSMNNGG-------CQHRCRNTFGSYQCS-CRN 781
            .||.::...||:..:           ...|........|       ||.:||. .|:.:.: |.:
Mouse   250 LSDLSLTADGFIGHYKFRPKKFPTTTTTPVTTTLPVTTGLKPTVALCQQKCRR-MGTLESNYCSS 313

  Fly   782 GYTLA 786
            .:.||
Mouse   314 NFVLA 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808
		Astacin	144..339	CDD:279708
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839	38/108 (35%)
		FXa_inhibition	595..630	CDD:291342	8/34 (24%)
		CUB	634..750	CDD:278839	43/116 (37%)
		FXa_inhibition	757..792	CDD:291342	9/38 (24%)
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
Pcolce2	NP_083896.1	CUB	32..142	CDD:238001	45/145 (31%)
		CUB	153..264	CDD:278839	43/116 (37%)
		NTR_PCOLCE	291..414	CDD:239631	8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.993157	Normalized mean entropy	S7146
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950