DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and tnfaip6

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_001035333.2	Gene:	tnfaip6 / 678516	ZFINID:	ZDB-GENE-060421-2654	Length:	271	Species:	Danio rerio

Alignment Length:	204	Identity:	56/204 - (27%)
Similarity:	84/204 - (41%)	Gaps:	45/204 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   757 CSMNNGGC----QHRCRNTFGSYQCSC------RNGYTLAENGHNC------------------- 792
            |:...|..    |.......|.:.|:.      |.||.:.:.|.||
Zfish    68 CNFEGGTLATFDQLEAARQIGFHVCAAGWLDKGRVGYPIVKAGSNCGFGKVGIIDYGYRLNKSER 132

  Fly   793 TETRCKFEITTSYG--------VLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQE 849
            .:..|...:....|        ||.||.||::|.....||||.:...||||:|.|.||::|...:
Zfish   133 WDVYCYNPVAKECGGVHTDPEKVLVSPGYPDEYQDEQICYWHIRVRFGHRIRLHFLDFDIEEDTD 197

  Fly   850 CIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVSECGGYL 914
            |:.|::.|||...:.|..:|.|||.:.|...|::.|.|.:...:|:.:...|||..::|
Zfish   198 CLSDHLEIYDSYDDVSGFVGRYCGDQLPDDFISTGNVMTLKFLSDSSVTAGGFKLQYIS------ 256

  Fly   915 RATNHSQTF 923
              .|.||.|
Zfish   257 --VNSSQLF 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808
		Astacin	144..339	CDD:279708
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342	9/44 (20%)
		CUB	797..906	CDD:278839	40/116 (34%)
		CUB	910..1023	CDD:278839	4/14 (29%)
tnfaip6	NP_001035333.2	Link_domain_TSG_6_like	46..138	CDD:239592	11/69 (16%)
tnfaip6	NP_001035333.2	CUB	145..254	CDD:278839	39/108 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900