DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and c6ast3

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_001013544.1	Gene:	c6ast3 / 541399	ZFINID:	ZDB-GENE-050320-99	Length:	255	Species:	Danio rerio

Alignment Length:	193	Identity:	63/193 - (32%)
Similarity:	102/193 - (52%)	Gaps:	22/193 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 IPYEIDTIFSGAHKALFKQAMRHWENFTCIKFV----ERDPNLHANYIYFTVKN-CGCCSFLGKN 210
            :||.|...:|.....:.::.:..:...|||:|.    |||        |.:::: .||.|::|:.
Zfish    79 VPYVIANHYSSRELEIIQRGLDSFSYSTCIRFFPRGNERD--------YISIESRSGCYSYVGRQ 135

  Fly   211 GNGRQPISIGRN-CEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEE 274
            |.. |.:|:.|: |.....:.|||.|.:||:||..|.|||.||.:...||:...:|||:.::...
Zfish   136 GYA-QTVSLARSGCLYHSTVQHELLHALGFNHEQTRNDRDNHIQVIWENILDDMKYNFNKVNTLN 199

  Fly   275 VDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKC 337
            ..   .|||.:|:|.|.:.:|||:. |.|:.||   |..:..||....:|:.||::.|.||:|
Zfish   200 QG---TPYDYSSVMQYERYAFSKNG-LPTMIPI---PNNNAALGTSTEMSQNDIIRINRLYQC 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	63/193 (33%)
		Astacin	144..339	CDD:279708	63/193 (33%)
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
c6ast3	NP_001013544.1	Astacin	68..255	CDD:279708	62/191 (32%)
c6ast3	NP_001013544.1	ZnMc	74..255	CDD:294052	62/191 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810