DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and ASTL

DIOPT Version :9

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:XP_011509507.1 Gene:ASTL / 431705 HGNCID:31704 Length:436 Species:Homo sapiens


Alignment Length:233 Identity:75/233 - (32%)
Similarity:118/233 - (50%) Gaps:29/233 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 QPIQRRRRAVTVRKERTWDYG-----VIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFV----E 184
            :|...|..:.|..|   |..|     .:|:.:.:.:....:.:..:|:..:|..|||:||    :
Human    85 RPSPFRLLSATSNK---WPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQ 146

  Fly   185 RDPNLHANYIYFTVKNCGCCSFLGKNGNGRQPISIGRNC--EKFGIIIHELGHTIGFHHEHARGD 247
            ||       ....:...||.|.:|::| |.|.:|:...|  :..||::|||.|.:||.|||.|.|
Human   147 RD-------FISIIPMYGCFSSVGRSG-GMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRAD 203

  Fly   248 RDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPG 312
            ||::|.:|...|:.|.|.||  :..:..:: |.|||.:|:|||.:.:||:.. |.||||:..|  
Human   204 RDRYIRVNWNEILPGFEINF--IKSQSSNM-LTPYDYSSVMHYGRLAFSRRG-LPTITPLWAP-- 262

  Fly   313 THLELGQRKRLSRGDIVQANLLYKCASCGRTYQQNSGH 350
             .:.:|||..||..||.:...||.|:..|...:....|
Human   263 -SVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSH 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808 70/211 (33%)
Astacin 144..339 CDD:279708 69/205 (34%)
CUB 388..474 CDD:214483
CUB 478..586 CDD:278839
FXa_inhibition 595..630 CDD:291342
CUB 634..750 CDD:278839
FXa_inhibition 757..792 CDD:291342
CUB 797..906 CDD:278839
CUB 910..1023 CDD:278839
ASTLXP_011509507.1 Astacin 97..288 CDD:279708 70/208 (34%)
ZnMc 105..286 CDD:294052 66/195 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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