DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and he1.2

DIOPT Version :10

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_998800.2 Gene:he1.2 / 407971 ZFINID:ZDB-GENE-030131-2100 Length:263 Species:Danio rerio


Alignment Length:235 Identity:80/235 - (34%)
Similarity:128/235 - (54%) Gaps:18/235 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   111 TDDAVDVLQHSHSPTLNGQPIQRRRRAVTVRKERT--WDYGV-----IPYEIDTIFSGAHKALFK 168
            |...::..:.|......|..:..:.|...:.::::  |....     :||.:...||...|::..
Zfish    39 TTQILETNKGSSEVLFEGDVVLPKNRNALICEDKSCFWKKNANNIVEVPYVVSGEFSINDKSVIA 103

  Fly   169 QAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKNGNGRQPISIGR-NCEKFGIIIHE 232
            .|:..:...|||:||.|  ::.|:|:....|: ||.|.:|:.| |:|.:|:.| .|...||..||
Zfish   104 NAISIFHAQTCIRFVPR--SIQADYLSIENKD-GCYSAIGRTG-GKQVVSLNRKGCVYSGIAQHE 164

  Fly   233 LGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSK 297
            |.|.:||:||.:|.|||:::.||..||..|..|||   ..::.:....|||..|:|||.|.:|:.
Zfish   165 LNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNF---LKQKTNNQNTPYDYGSLMHYGKTAFAI 226

  Fly   298 SPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKC 337
            .|.|:|||||   |..::::|||:.||:.||::.|.||.|
Zfish   227 QPGLETITPI---PDENVQIGQRQGLSKIDILRINKLYGC 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808 76/209 (36%)
CUB 388..474 CDD:214483
CUB 478..586 CDD:395345
FXa_inhibition 595..630 CDD:464251
CUB 634..750 CDD:395345
FXa_inhibition 757..792 CDD:464251
CUB 797..906 CDD:395345
CUB 910..1023 CDD:395345
he1.2NP_998800.2 ZnMc_hatching_enzyme 81..263 CDD:239810 74/191 (39%)
Blue background indicates that the domain is not in the aligned region.

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