DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and CG10280

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_001246942.1	Gene:	CG10280 / 40740	FlyBaseID:	FBgn0037395	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	71/211 - (33%)
Similarity:	109/211 - (51%)	Gaps:	28/211 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 ERTWDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVK-----NCG 202
            :|.|..|.||:||...::...:....||::.:.:.||:.||..|..:..   |..::     ..|
  Fly   146 KRLWPNGTIPFEISPRYANQERQAIIQAVKTFNSLTCVHFVPYDGEVDD---YLLIEPPLEGPQG 207

  Fly   203 CCSFLGKNGNGRQPISIGRNCEKF-------GIIIHELGHTIGFHHEHARGDRDKHIVINKGNIM 260
            |.|::|:.| |.|.:|:.|..|..       |.|:|||.|.||.:||.:|.|||..:.|:..||:
  Fly   208 CWSYVGRRG-GEQVVSLQRPDENSAHCFSSEGRIMHELMHAIGIYHEQSRADRDNFVKIHWDNIV 271

  Fly   261 RGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSK----SPYLDTITPIGIPPGTHLELGQRK 321
            .....||.::|.::... ...||.||:|||.:..|||    .|   |:||  :.||  :.:||||
  Fly   272 PRFRKNFKLVSKKKGKY-AFDYDYNSVMHYGEFYFSKRKGEKP---TMTP--LQPG--VRIGQRK 328

  Fly   322 RLSRGDIVQANLLYKC 337
            .:|:.|.::.|.||.|
  Fly   329 TISKIDCLKINELYGC 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	71/211 (34%)
		Astacin	144..339	CDD:279708	71/210 (34%)
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
CG10280	NP_001246942.1	Astacin	147..344	CDD:279708	70/208 (34%)
CG10280	NP_001246942.1	ZnMc_astacin_like	151..342	CDD:239807	66/202 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840