DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and pcolce2b

DIOPT Version :9

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_956754.1 Gene:pcolce2b / 393432 ZFINID:ZDB-GENE-040426-1177 Length:413 Species:Danio rerio


Alignment Length:333 Identity:98/333 - (29%)
Similarity:150/333 - (45%) Gaps:67/333 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   471 KARFEVVCGGDLKLTKDQS-IDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAY 534
            ::|....|||:  :|.:.. |.|..||..|.|:.:||||||.|:.....|.|:..:||..:.|.|
Zfish    21 QSRQSFTCGGN--ITGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVAVLTFRFLDLESDNLCRY 83

  Fly   535 DFVEIRDGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTD 599
            |:|::..| |.:.:.:|||||...|..:.:.||:|.::.|||:                      
Zfish    84 DYVDVYSG-HGNGQRLGRFCGTFRPGALVSTSNKMLMQMVSDA---------------------- 125

  Fly   600 HGCQHLCINTLGSYQCGCRAGYELQANGKTCEDACGGVVDATKSNGSLYSPSYPD-VYPNSKQCV 663
                    ||.||   |..|.|......:..:..|||.:  .|.:||..:|::|: .||....|.
Zfish   126 --------NTAGS---GFLAVYSAANPNERGDQYCGGRL--MKPSGSFKTPNWPERDYPAGVTCS 177

  Fly   664 WEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQ 728
            |.:|||.|..:.:.|..||:|  |.:|  |.|||:.|::....|..|:||.|||...|..|.||.
Zfish   178 WHIVAPKNQIIEVKFEKFDVE--RDNY--CRYDYVAIFNGGEINDAKRIGKYCGDTPPAPVFSEG 238

  Fly   729 SILRLEFYSDRTVQRSGFVAKFVIDVDE---------------------CSMNNGGCQHRC--RN 770
            :.|.::|.||.::...||:..:.....:                     ...:...||.:|  :.
Zfish   239 NQLFIQFLSDLSLTADGFIGHYKFRPKKFPSTTVPPTTTAPPTTTRPTPLKYSAALCQQKCKRKG 303

  Fly   771 TFGSYQCS 778
            |..|:.||
Zfish   304 TPESHYCS 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
Astacin 144..339 CDD:279708
CUB 388..474 CDD:214483 0/2 (0%)
CUB 478..586 CDD:278839 39/108 (36%)
FXa_inhibition 595..630 CDD:291342 7/34 (21%)
CUB 634..750 CDD:278839 44/116 (38%)
FXa_inhibition 757..792 CDD:291342 7/24 (29%)
CUB 797..906 CDD:278839
CUB 910..1023 CDD:278839
pcolce2bNP_956754.1 CUB 28..138 CDD:238001 46/145 (32%)
CUB 149..260 CDD:278839 44/116 (38%)
NTR_PCOLCE 290..413 CDD:239631 7/22 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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