DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and CG15253

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	62/196 - (31%)
Similarity:	95/196 - (48%)	Gaps:	8/196 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 WDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKN 210
            |...:|.|.|::.....|:.....|::..|:.:|:.|.|...: ...|:..|.:..||.|::|..
  Fly    57 WPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTD-QKYYVNVTSEEGGCFSYIGYL 120

  Fly   211 GN----GRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLS 271
            ..    ..|...||..|.:...|:||..|.:||.|:.:..|||.::.|.:.||..|.|:|||..:
  Fly   121 NRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYT 185

  Fly   272 PEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYK 336
            .|.|:.....||..|:|||...:|||:   ...|.:.:..|....:|||..||..||.:.|.:||
  Fly   186 EETVNDFGEKYDYGSVMHYGPYAFSKN---GERTILALEEGKEDVIGQRLELSETDIRKLNAIYK 247

  Fly   337 C 337
            |
  Fly   248 C 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	62/196 (32%)
		Astacin	144..339	CDD:279708	62/196 (32%)
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	62/196 (32%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	58/190 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444932
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840