DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and Tnfaip6

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_033424.1	Gene:	Tnfaip6 / 21930	MGIID:	1195266	Length:	275	Species:	Mus musculus

Alignment Length:	189	Identity:	50/189 - (26%)
Similarity:	74/189 - (39%)	Gaps:	37/189 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   757 CSMNNGGC----QHRCRNTFGSYQCSC------RNGYTLAENGHNC------------------- 792
            |....|..    |.......|.:.|:.      |.||.:.:.|.||
Mouse    58 CEFEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSER 122

  Fly   793 --------TETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQE 849
                    ....|....|....:.:||.:|.:|..|..||||.:...|.||.|:|.||::|....
Mouse   123 WDAYCYNPHAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPG 187

  Fly   850 CIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVS 908
            |:.|||.|||...:....:|.|||...|..:|::.|.|.:...:||.:...||:..:|:
Mouse   188 CLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVT 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808
		Astacin	144..339	CDD:279708
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342	9/44 (20%)
		CUB	797..906	CDD:278839	38/108 (35%)
		CUB	910..1023	CDD:278839
Tnfaip6	NP_033424.1	Link_domain_TSG_6_like	36..128	CDD:239592	11/69 (16%)
		CUB	135..244	CDD:278839	38/108 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	253..275
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900