DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and clec-9

DIOPT Version :10

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_507227.2 Gene:clec-9 / 190567 WormBaseID:WBGene00013493 Length:414 Species:Caenorhabditis elegans


Alignment Length:441 Identity:86/441 - (19%)
Similarity:151/441 - (34%) Gaps:127/441 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   514 NHQVALKFQSFELEKHDGC-AYDFVEIRDGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDS 577
            ||:.|          .:.| :||...:...|..|:|.:..|.|:                  :.|
 Worm    42 NHRAA----------ENSCFSYDATLVTVKNSIDNRAVSTFVGN------------------AAS 78

  Fly   578 SVQKLGFSAALMLDVDECKFTD------------HGCQHL----C--INTLGS-----YQCGCRA 619
            |:....|  ...:||..|.:.|            :|...:    |  |:.:||     |...|  
 Worm    79 SIWMGLF--CFNMDVTNCLWDDGNGTAQGYNNFMNGSPQIESGKCVYISLMGSSSGRWYSGNC-- 139

  Fly   620 GYELQANGKTC------EDACGGVVDATKSNGSLYSPSYPDVYPNSK-----QC--VWEVVAPPN 671
              :|.:....|      ||.|     :...||..||.:.|..:..::     ||  :..:::|..
 Worm   140 --DLDSRPFVCELPITFEDDC-----SNNYNGFCYSYNPPASFVRAQQNCENQCGSIVSILSPNE 197

  Fly   672 H----AVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCG-----HELPPVVNSE 727
            :    |:|..:...|:.......||..|.:                 :.|     :::.|....:
 Worm   198 NRYVGALFPRYESNDMIIGATWTTKDTYSW-----------------FDGSPWNFNQINPASPKK 245

  Fly   728 QSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTFGSYQCSCRNGYTLA---ENG 789
            ..:..:...:|.:...|.:..       .|....|   :.|:...| .||......|:.   .|.
 Worm   246 NCLAMVTSLNDASASGSWYPI-------VCYSAYG---YLCKRPAG-VQCPQYPPVTVTPAPSNP 299

  Fly   790 HNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQECIYDY 854
            ..|..|      ..|:|.:.|||:|.:|.....|.:...|:..:.:.|.|:.|..:...    |:
 Worm   300 SGCNST------IMSFGTITSPNFPMNYNNITSCNYLLTTLGSYNVMLKFNKFYTDMKN----DF 354

  Fly   855 VAIYDGRSENSSTLGIYCGGRE-PYAVIASTNEMFMVLATDAGLQRKGFKA 904
            |.:|||.|..|..:..|.|..| |:..:::.|.|.:...:::.....||.|
 Worm   355 VTLYDGDSTKSPVIAKYSGYYEWPFFNVSTGNSMLVTFRSNSTFGYYGFTA 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
CUB 388..474 CDD:214483
CUB 478..586 CDD:395345 14/72 (19%)
FXa_inhibition 595..630 CDD:464251 10/57 (18%)
CUB 634..750 CDD:395345 19/131 (15%)
FXa_inhibition 757..792 CDD:464251 8/37 (22%)
CUB 797..906 CDD:395345 28/109 (26%)
CUB 910..1023 CDD:395345
clec-9NP_507227.2 CLECT 22..149 CDD:214480 26/140 (19%)
CLECT 162..277 CDD:214480 20/141 (14%)
CUB 302..409 CDD:238001 30/114 (26%)
Blue background indicates that the domain is not in the aligned region.

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