Protein Alignment tld and nas-22

DIOPT Version :9

• Sequence 1: NP_524487.2
• Gene: tld / 42945
• FlyBaseID: FBgn0003719
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_505908.2
• Gene: nas-22 / 188423
• WormBaseID: WBGene00003541
• Length: 367
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 93/443 - (20%)
• Similarity: 146/443 - (32%)
• Gaps: 137/443 - (30%)

  Fly   133 RRRRAVTVR-----KERTWDYGVIPYEI-DTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHA 191
            |.||.|.:|     :...|....:.|.. :..|....|....:||....|.||||| ..:|:..:
 Worm    36 RHRRQVLIRGSDEERRHKWFNNTVHYYFYEENFDFTVKESILRAMELISNHTCIKF-STEPSEKS 99

  Fly   192 NYIYFTVKNCGCCSFLGKNGNGRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINK 256
            ..:........|.:.:|: ....|..|...:|...|:.:|||.|::||.|.|.|.|||:::...|
 Worm   100 IRMESDSTTIACYAEIGQ-VRENQLFSFNSDCYSAGVAVHELIHSLGFIHAHQRSDRDQYLEFKK 163

  Fly   257 GNIMRGQEY--NFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQ 319
            ......|.|  .:.:...:|:   |:|||:.|:|.| .|...:..|     |:
 Worm   164 NLDELNQTYQEQYKIWEYQEI---LVPYDVGSVMQY-PNEEDEEYY-----PV------------ 207

  Fly   320 RKRLSRG-----------DIVQANLLYKCASCGRTYQQNSGHIVSPHFIYSGNGVLSEFEGSGDA 373
            ||..:..           |.:..|..|:|:.......:|.|:
 Worm   208 RKYRTMANTMGSAIVAFYDYLMINKYYECSCANNLSCKNHGY----------------------- 249

  Fly   374 GEDPSAESEFDASLTNCEWRITATNGEKVILHLQQLHLMSSDDCTQDYLEIRDGYWHKSPLVRRI 438
             .:||     :.|..||.:.                  ....||:|                |..
 Worm   250 -PNPS-----NCSQCNCPYG------------------FGGADCSQ----------------RAE 274

  Fly   439 CGNVSGEVITTQTSRMLLNYVNRNAAKGYRGFKARFEVVCGGDLKLTKDQSIDSPNYPMDYMPDK 503
            .|.......|.|...:.|:       .|||              .|..:|.:...::...::
 Worm   275 PGATFQATETWQNVTISLD-------AGYR--------------YLENNQKLPQVDFIYQFL--- 315

  Fly   504 ECVWRITAPDNHQVALKFQSF-ELEKHDGCAYDFVEIRDGNHSDSRLIG-RFC 554
               | |.||.|....::.:.| |.:...||....|||:  .:.|.||.. |.|
 Worm   316 ---W-IMAPANKTTQIRVEKFVEGKCLPGCIRGGVEIK--TNEDPRLTSPRLC 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	52/219 (24%)
		Astacin	144..339	CDD:279708	51/208 (25%)
		CUB	388..474	CDD:214483	13/85 (15%)
		CUB	478..586	CDD:278839	19/79 (24%)
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
nas-22	NP_505908.2	ZnMc	50..192	CDD:214576	39/146 (27%)
		ZnMc	56..234	CDD:294052	48/200 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810