DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and nas-19

DIOPT Version :9

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_505893.2 Gene:nas-19 / 186926 WormBaseID:WBGene00003538 Length:396 Species:Caenorhabditis elegans


Alignment Length:226 Identity:57/226 - (25%)
Similarity:95/226 - (42%) Gaps:46/226 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 WDYGVIPY-------EIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGC 203
            |.|||:.|       ||        |.:.:.|:.:..|.|||:|.| |.|..........:|..|
 Worm    50 WSYGVVNYYYADKNNEI--------KEMVESAIAYIANHTCIRFNE-DQNAVQRVQIRMQQNWLC 105

  Fly   204 CSFLGKNG-NGRQPIS----IGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQ 263
            .|.:|..| :..:||.    :.::|:..|.|:||..|::|..|||.|.|||..:.:.. .:...:
 Worm   106 QSTVGAPGMSMSKPIGELSMLVQSCDTIGSIVHEFSHSLGRFHEHTRPDRDNFMKVTT-TVHEAR 169

  Fly   264 EYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQR-----KRL 323
            .      .|..:.....|::..|:|.|         :.||..|..:.|   |::..:     :|:
 Worm   170 P------RPSGMTTMYGPFEHGSVMMY---------HADTYGPGTMDP---LDMDYKQTMGNRRV 216

  Fly   324 SRGDIVQANLLYKCASCGRTYQQNSGHIVSP 354
            :..|:.:.|..|.| .|.:..:..:|...||
 Worm   217 TFYDMYKINQYYGC-WCSKQLECKNGGYTSP 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808 52/208 (25%)
Astacin 144..339 CDD:279708 53/209 (25%)
CUB 388..474 CDD:214483
CUB 478..586 CDD:278839
FXa_inhibition 595..630 CDD:291342
CUB 634..750 CDD:278839
FXa_inhibition 757..792 CDD:291342
CUB 797..906 CDD:278839
CUB 910..1023 CDD:278839
nas-19NP_505893.2 Astacin 48..230 CDD:279708 52/207 (25%)
ZnMc 53..228 CDD:294052 49/202 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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