Protein Alignment tld and nas-29

DIOPT Version :9

• Sequence 1: NP_524487.2
• Gene: tld / 42945
• FlyBaseID: FBgn0003719
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_494953.3
• Gene: nas-29 / 186488
• WormBaseID: WBGene00003547
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 124/550 - (22%)
• Similarity: 188/550 - (34%)
• Gaps: 203/550 - (36%)

  Fly   123 SPTLNG-----QPIQRRRRAVTVRKERT-----------------WDYGVIPYEIDTIFSGAHKA 165
            |..:||     :.|:.|||...:..|.|                 |..||.....:::...|..|
 Worm   102 SMIVNGSTEYRKAIKSRRRGNKINGESTDRTKRQAYLDNNYPATIWKNGVAFMFHESLTPIAKTA 166

  Fly   166 LFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKNGN-GRQPISIGRNCEKFGII 229
            :.| |:..|...|||:|..|  .....|:.|...:.||.|.:|::.: |:|.:|||..||.||:.
 Worm   167 ILK-AVHFWYRETCIEFHPR--TFQKEYLLFIGNDDGCWSTVGRDASQGKQVVSIGNGCEHFGVT 228

  Fly   230 IHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNS 294
            .|||.|.:|..||.:|.|||:.:|.|...:.|...:||..:||.::....||||:.|:|||....
 Worm   229 SHELAHALGIFHEQSRFDRDESVVFNPRVVERDLLFNFAKISPRQMSTYGLPYDIGSVMHYTPTE 293

  Fly   295 FSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKCASCGRTYQQNSGHIVSPHFIYS 359
            ||..|.:.|:..|                      ..||           ||..|.:..|.|
 Worm   294 FSNIPSIPTLAAI----------------------DTNL-----------QQTMGQLEGPSF--- 322

  Fly   360 GNGVLSEFEGSGDAGEDPSAESEFDASLTNCEWRITATNGEKVILHLQQLHLMSSDDC-TQDYLE 423
                                                      |.:|:...|....:.| ||
 Worm   323 ------------------------------------------VDVHIMNQHYQCQEKCPTQ---- 341

  Fly   424 IRDGYWHKSPLVRRICGNVSGEVITTQTSRMLLNYVNRNAAKGYRGF--------KARFEVVCGG 480
                    :|     |.|..           ..|..|....|...||        .:.|...|||
 Worm   342 --------AP-----CQNGG-----------FTNSRNCKVCKCPTGFGGAYCQLIASSFSPFCGG 382

  Fly   481 DLK---------LTKDQSIDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDF 536
            .|.         :|..||..:.:        |.||:.|.||:..::.:.....:.:..:||..|.
 Worm   383 YLNAEETTRRFDITIRQSTTTRS--------KTCVYHIKAPEGKRIIIDILKIDSKCIEGCWQDG 439

  Fly   537 VEIRDGNHSDSRLIG-RFC------------GDKLPPNIKTRSNQMYIR---------------- 572
            :|::  ...|.|.:| |||            |:.:|..:.::.:...:.
 Worm   440 LELK--MKKDFRPVGYRFCCPESSRRKVISEGNMVPFMVFSKEHDFSVSFEYSFVSTSAGFDDEK 502

  Fly   573 -------------FVSDSS-VQKLGFSAAL 588
                         ||||:| :|::||...|
 Worm   503 NDSDVIVDNLDGVFVSDTSLLQRIGFRRQL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	63/218 (29%)
		Astacin	144..339	CDD:279708	62/212 (29%)
		CUB	388..474	CDD:214483	14/94 (15%)
		CUB	478..586	CDD:278839	33/159 (21%)
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
nas-29	NP_494953.3	Astacin	145..336	CDD:279708	69/271 (25%)
		ZnMc_astacin_like	148..332	CDD:239807	67/264 (25%)
		CUB	404..491	CDD:214483	18/96 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810