DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and clec-18

DIOPT Version :10

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_493109.1 Gene:clec-18 / 186419 WormBaseID:WBGene00010169 Length:408 Species:Caenorhabditis elegans


Alignment Length:463 Identity:105/463 - (22%)
Similarity:156/463 - (33%) Gaps:146/463 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   502 DKECVWRITAPDNHQVALKFQSFELEKHDGCA---YDFVEIRDGNHSDSRLI------------- 550
            :.:|:...:.|.|||        |.||  .|:   ...|.:::.|  ||:.|             
 Worm    33 NNKCLKLFSTPSNHQ--------EAEK--SCSRFGATLVTVKNAN--DSQAISTITKSSAPLVWL 85

  Fly   551 GRFCGDKLPPNI----KTRSNQMYIRFVSDSSVQKLG----FS-----AALMLDVDEC------- 595
            |.:|.|..|...    .|.|..|:..|.:...:.:||    :|     |...|:.| |       
 Worm    86 GLYCFDNYPSRCLWDDGTGSAHMFSNFSNGFPLVQLGNCVYYSTRGVLAEKWLNSD-CAGNRMAY 149

  Fly   596 ------KFTDHGCQH----LCINTLGSYQCGCRAGYELQANGKTCEDACGGVVDATKSNGSLYSP 650
                  .|.|: |.|    .|. |:..|     |...|:|. ::|:...|.:|.....|.:.|..
 Worm   150 ICELPPTFKDN-CTHNYNGFCY-TISQY-----AKVPLKAQ-ESCQKEGGNLVSIHSENENRYIN 206

  Fly   651 SYPDVYPNSKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIY 715
            :...|........|.         |.|...: ::||...||  |.|.|      ..||:.    |
 Worm   207 TIAPVVDYFIGATWN---------FYNILKW-IDGTDMQYT--NIDLL------NSNRVD----Y 249

  Fly   716 CGHELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTFGSYQCSCR 780
            |   ......|..:.....:||                 .:||:..   |:.|:...| .|||  
 Worm   250 C---TAMATKSGGAHSTGSWYS-----------------ADCSITK---QYICKRRAG-VQCS-- 288

  Fly   781 NGYTLAENGHNCTET----------RCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRI 835
                       .|.|          .|...|..:.||:.|.|    ...::.|.:...|:..::|
 Worm   289 -----------MTSTTAIPFPEIPSNCNVGIQMAPGVINSRN----LSGSVNCTYQLATLGPYKI 338

  Fly   836 QLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRK 900
            .|.|..|:..:      |||.||||.|..|..||.|.|....:...:|.:.|.:...:|....:.
 Worm   339 ALKFTFFDTGN------DYVTIYDGPSTESPILGRYSGNMYEFTRTSSGSTMVVTFKSDGFGNQS 397

  Fly   901 GFKATFVS 908
            ||.|.|.|
 Worm   398 GFNAGFSS 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
CUB 388..474 CDD:214483
CUB 478..586 CDD:395345 25/112 (22%)
FXa_inhibition 595..630 CDD:464251 11/51 (22%)
CUB 634..750 CDD:395345 22/115 (19%)
FXa_inhibition 757..792 CDD:464251 8/34 (24%)
CUB 797..906 CDD:395345 31/108 (29%)
CUB 910..1023 CDD:395345
clec-18NP_493109.1 CLECT 25..152 CDD:214480 29/131 (22%)
CLECT 165..280 CDD:214480 32/166 (19%)
CUB 312..405 CDD:238001 30/102 (29%)
Blue background indicates that the domain is not in the aligned region.

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