DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and nas-15

DIOPT Version :9

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_508154.2 Gene:nas-15 / 180426 WormBaseID:WBGene00003534 Length:571 Species:Caenorhabditis elegans


Alignment Length:221 Identity:78/221 - (35%)
Similarity:111/221 - (50%) Gaps:14/221 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 WDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKN 210
            |..|.|||.|.:.:|...::|...:|:.:.:.|||::|.::. ...||::. ..:.||.|.:||.
 Worm   123 WPEGRIPYTISSQYSSYSRSLIAASMQEYASHTCIRWVPKEA-ADVNYVHI-YPDRGCYSMVGKM 185

  Fly   211 GNGRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEV 275
            | |:|.:|:|..|.:.|||:|||.|.:||.||.:|.|||.||.|...||..|.:..|:......:
 Worm   186 G-GKQSLSLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQGQFEKYGHGTI 249

  Fly   276 DLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKCASC 340
            ......||..|||||...:||::.     .|..||......:|||...|:.|..:.|.||.|...
 Worm   250 QSLGTGYDYGSIMHYGTKAFSRNG-----QPTMIPKKNGATIGQRNGFSKVDKFKINTLYGCPVE 309

  Fly   341 GR---TYQQNSGHI---VSPHFIYSG 360
            |.   |....||.|   |.|..|.:|
 Worm   310 GEKPTTSAPTSGPIVITVKPVVITTG 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808 68/191 (36%)
Astacin 144..339 CDD:279708 69/192 (36%)
CUB 388..474 CDD:214483
CUB 478..586 CDD:278839
FXa_inhibition 595..630 CDD:291342
CUB 634..750 CDD:278839
FXa_inhibition 757..792 CDD:291342
CUB 797..906 CDD:278839
CUB 910..1023 CDD:278839
nas-15NP_508154.2 Astacin 121..308 CDD:279708 69/192 (36%)
ZnMc_astacin_like 126..304 CDD:239807 65/185 (35%)
ShKT 354..388 CDD:214586
ShK 436..471 CDD:279838
Gag_MA <472..531 CDD:279482
ShK 535..571 CDD:279838
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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