DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and clec-5

DIOPT Version :10

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_498022.1 Gene:clec-5 / 175652 WormBaseID:WBGene00016450 Length:419 Species:Caenorhabditis elegans


Alignment Length:411 Identity:91/411 - (22%)
Similarity:150/411 - (36%) Gaps:129/411 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   550 IGRFCGD----KLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDEC-----------KFTD 599
            ||.:|.|    |...:..|.|.:||..|.|       ||.   ::|:.:|           |:.:
 Worm    83 IGLYCFDNDVTKCLWDDSTGSAEMYNSFAS-------GFP---LVDIGKCVYYSTQGSLAGKWLN 137

  Fly   600 HGCQ-----HLC-------INTLGSYQCGCRAGYELQANGKT-------CEDACGGVVDATKSNG 645
            ..|:     .:|       .|...:|...|   :.|.....|       ||..||.:.....||.
 Worm   138 GNCESDPRAFVCELPATHADNCTYNYNGHC---FTLHTERNTFVQAQAICEQECGNLASIHSSNE 199

  Fly   646 SLYSPSYPDVYPN-SKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRL 709
            :.|..|......| |...|:...:.|:.:|| |:    |:|:...||..:..:            
 Worm   200 NRYLSSIMSSIMNLSNSSVYIGASWPSSSVF-NW----LDGSNSDYTNIDQSF------------ 247

  Fly   710 KKIGIYCGH--ELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTF 772
                   ||  ....:.|.:.|::.:.::.                                   
 Worm   248 -------GHGGNCALLSNYQPSVVPMGYWF----------------------------------- 270

  Fly   773 GSYQCSCRNGYTLAEN-GHNCTETR--------------CKFEITTSYGVLQSPNYPEDYPRNIY 822
             |:.|:....:....: |..|:.|.              |...:..:.||:.|||||.:|..|.:
 Worm   271 -SFPCTAAVPFICKRSAGIKCSGTPPPVTVTPVPSNPSFCNSTLLIAPGVITSPNYPSNYDNNQF 334

  Fly   823 CYWHFQTVLGHRIQLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEM 887
            |.:|..|:..:|:.|.|..|..|.:    :|.|.:|:|.|.:||.:|.|.|..:|::|:::.|.|
 Worm   335 CSYHLSTLGSYRVLLHFSAFATEVN----FDLVVVYNGESASSSQIGRYSGSLDPFSVVSTGNNM 395

  Fly   888 FMVLATDAGLQRKGFKATFVS 908
            |:...||.....:||.|.|.|
 Worm   396 FVTFKTDGSGVAQGFSARFTS 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
CUB 388..474 CDD:214483
CUB 478..586 CDD:395345 13/39 (33%)
FXa_inhibition 595..630 CDD:464251 9/64 (14%)
CUB 634..750 CDD:395345 21/118 (18%)
FXa_inhibition 757..792 CDD:464251 3/35 (9%)
CUB 797..906 CDD:395345 38/108 (35%)
CUB 910..1023 CDD:395345
clec-5NP_498022.1 CLECT 23..150 CDD:214480 17/76 (22%)
CLECT 163..283 CDD:214480 29/182 (16%)
CUB 309..416 CDD:238001 39/110 (35%)
Blue background indicates that the domain is not in the aligned region.

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