DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tld and clec-10

DIOPT Version :10

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:NP_493725.2 Gene:clec-10 / 173430 WormBaseID:WBGene00015403 Length:415 Species:Caenorhabditis elegans


Alignment Length:466 Identity:110/466 - (23%)
Similarity:157/466 - (33%) Gaps:145/466 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   486 KDQSIDSPNYPMDYMPDKECVWRITAPDNHQVA----------LKFQSFELEKHDGCAYDFVEIR 540
            :|..:...||....:..|      .|.||..||          |....|| :....|.:|     
 Worm    46 RDAELSCRNYGATLVTVK------NAQDNQDVATIAGSAKLIWLGLSCFE-DSFGKCFWD----- 98

  Fly   541 DGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHGCQ-- 603
            |.:.| :.....|.|..  ||::......|       |.|  |..|.        |:....|:  
 Worm    99 DASGS-ANSYNSFSGGY--PNVQVGQCVYY-------STQ--GVLAG--------KWISEDCERY 143

  Fly   604 ---HLC-INTLGSYQCGCRAGYELQANG----------------KTCEDACGGVVDATKSNGSLY 648
               ::| :.|  :||..|...|    ||                |.||.:||.:|       |::
 Worm   144 RMPYICELPT--TYQDSCSYNY----NGYCYTFSSTAVPFVTAQKICELSCGNLV-------SIH 195

  Fly   649 SPSYPDVYPNSKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYT-KCNYDYLII------YSKMRD 706
            |       ||..|.:            :||:.|..:|.....| |.||....:      |.::..
 Worm   196 S-------PNELQYI------------VNFAPFVDDGYFIGATWKNNYSLSWLDDSPWDYDRIDP 241

  Fly   707 NRLKKIG----IYCGHELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHR 767
            :...|:|    ||.|      |.|:   :...:||                ||...:.|   |:.
 Worm   242 SFSVKVGYCFTIYTG------VGSK---ITGSWYS----------------VDNWEIPN---QYI 278

  Fly   768 CRNTFGSYQCSCRNGYTLAENGHNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLG 832
            |:...| ..||.....|...|..||...|..:.     ||..|||||.:|..|..|.:...|:..
 Worm   279 CKIPAG-VPCSPAPPVTPTPNLSNCNGPRMMYS-----GVFTSPNYPNNYDNNEDCTYLISTLGP 337

  Fly   833 HRIQLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGL 897
            :.|.|....|..| |:   ||.|.||||.:.:...|....|......:.:|.|.:.:...:|...
 Worm   338 YGIFLFIAPFSTE-HK---YDVVTIYDGPTTSHKVLAHLSGEIGISMMTSSGNSLLVTFKSDKTN 398

  Fly   898 QRKGFKATFVS 908
            ...||.|.|.|
 Worm   399 TFSGFSARFYS 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
CUB 388..474 CDD:214483
CUB 478..586 CDD:395345 24/109 (22%)
FXa_inhibition 595..630 CDD:464251 11/56 (20%)
CUB 634..750 CDD:395345 26/126 (21%)
FXa_inhibition 757..792 CDD:464251 8/34 (24%)
CUB 797..906 CDD:395345 31/108 (29%)
CUB 910..1023 CDD:395345
clec-10NP_493725.2 CLECT 24..150 CDD:214480 27/135 (20%)
CLECT 163..280 CDD:214480 36/174 (21%)
CUB 302..409 CDD:238001 34/115 (30%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.