DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tld and tnfaip6

DIOPT Version :9

Sequence 1:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	XP_002936705.2	Gene:	tnfaip6 / 100490996	XenbaseID:	XB-GENE-988687	Length:	269	Species:	Xenopus tropicalis

Alignment Length:	125	Identity:	37/125 - (29%)
Similarity:	62/125 - (49%)	Gaps:	3/125 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   784 TLAENGHNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQ 848
            |...|.|:   ..|...:|....:::||.||.:|..:..||||.:...|.|:.:.|.|.::|...
Frog   125 TYCYNPHS---KECGGVLTEPERIIKSPGYPNNYENDQICYWHIRVNYGQRVFIEFLDIDIEEDI 186

  Fly   849 ECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVS 908
            :|:.||..|||...:....:|.|||...|.::|::.|.|.:...||..:...||:..:.:
Frog   187 DCLSDYFEIYDSYDDIHGLVGRYCGYELPDSIISTGNVMTLKFLTDRSVSGGGFQIKYTA 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808
		Astacin	144..339	CDD:279708
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342	3/7 (43%)
		CUB	797..906	CDD:278839	34/108 (31%)
		CUB	910..1023	CDD:278839
tnfaip6	XP_002936705.2	Link_domain_TSG_6_like	36..128	CDD:239592	1/2 (50%)
tnfaip6	XP_002936705.2	CUB	135..244	CDD:395345	34/108 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000