Protein Alignment tld and hce2l2

DIOPT Version :10

• Sequence 1: NP_524487.2
• Gene: tld / 42945
• FlyBaseID: FBgn0003719
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: XP_001342763.2
• Gene: hce2l2 / 100003133
• ZFINID: ZDB-GENE-070912-146
• Length: 276
• Species: Danio rerio
• Alignment Length: 270
• Identity: 84/270 - (31%)
• Similarity: 131/270 - (48%)
• Gaps: 42/270 - (15%)

  Fly    87 GRRRKQSHK---SQNKAALRLPPPFLWTDDAVDVLQHSHSPTLNGQPIQRRRRAVTVRKERT--- 145
            |.||::|:.   .:|:.|:         |..:||..:....:::|..::....||:.|.::.
Zfish    27 GARRQRSYSEDIEENQTAM---------DRIIDVNDYQGVFSVDGTNLREGDIAVSGRSQKNCFA 82

  Fly   146 ----WDYGV-----IPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLH-ANYIYFTVKN 200
                |...|     |.|.:...:..|.....|:.|...|..||::||   |..| .:|:....|.
Zfish    83 RSCLWTKSVDGNVYIAYSLSHAYDDADVKNIKEGMELIEQDTCVRFV---PRTHQRDYLDIQPKT 144

  Fly   201 CGCCSFLGKNGNGRQPISI-GRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQE 264
             ||.|:||..| |||.||: ..:|...|:.:|||.|.:||.||.:|.||||::.|...||.:.:.
Zfish   145 -GCWSYLGARG-GRQTISLQSPDCTGSGVTVHELMHALGFVHEQSRADRDKYVTIMWSNIWKDRL 207

  Fly   265 YNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSK--SPYLDTITPIGIPPGTHLELGQRKRLSRGD 327
            .||:......:|   .|||.:|:||:.|.:||:  .|   ||.|   ....::::|||...|..|
Zfish   208 RNFEKFKTNNLD---TPYDYSSVMHFGKYAFSEDGEP---TIVP---KRNWNVKIGQRLGPSDLD 263

  Fly   328 IVQANLLYKC 337
            |::.|.||.|
Zfish   264 IMKINKLYSC 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	74/217 (34%)
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:395345
		FXa_inhibition	595..630	CDD:464251
		CUB	634..750	CDD:395345
		FXa_inhibition	757..792	CDD:464251
		CUB	797..906	CDD:395345
		CUB	910..1023	CDD:395345
hce2l2	XP_001342763.2	ZnMc_hatching_enzyme	92..273	CDD:239810	68/194 (35%)