DRSC/TRiP Functional Genomics Resources

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Protein Alignment tld and pcolce2a

DIOPT Version :9

Sequence 1:NP_524487.2 Gene:tld / 42945 FlyBaseID:FBgn0003719 Length:1067 Species:Drosophila melanogaster
Sequence 2:XP_009295891.1 Gene:pcolce2a / 100002838 ZFINID:ZDB-GENE-070705-25 Length:415 Species:Danio rerio


Alignment Length:327 Identity:95/327 - (29%)
Similarity:145/327 - (44%) Gaps:68/327 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   478 CGGDLKLTKDQS-IDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDFVEIRD 541
            |||:  .|.|.. |.|..||..|.|:.:||||||.|....|:|.|:..:||....|.||||::.|
Zfish    29 CGGN--FTGDTGMIGSQGYPAVYPPNNKCVWRITVPQGRLVSLLFRVLDLESDSLCRYDFVDVYD 91

  Fly   542 GNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHGCQHLC 606
            | |.:.:.:|||||...|..:.|..|:|.:..|||:                             
Zfish    92 G-HINGQRLGRFCGTAKPRALVTNGNKMQVVMVSDA----------------------------- 126

  Fly   607 INTLGSYQCGCRAGYELQANGKTCEDACGGVVDATKSNGSLYSPSYPDV-YPNSKQCVWEVVAPP 670
             ||.||   |..|.|......:..:..|||::|  |.:|::.:|::||. ||....|.|.:|||.
Zfish   127 -NTAGS---GFLAVYSAIRPNERVDRYCGGLLD--KPSGTIKTPNWPDKDYPPGVTCSWHIVAPL 185

  Fly   671 NHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQSILRLEF 735
            :..:.|.|..||:|    ..:.|.||::.:::....|..:|||.:||...|..::|:...|.:.|
Zfish   186 DQIIELKFEKFDVE----RDSNCRYDHVAVFNGGETNETRKIGKFCGDSPPMPIHSDGHHLLITF 246

  Fly   736 YSDRTVQRSGFVAKFVI-----DVDECSMNNGG-----------------CQHRCR--NTFGSYQ 776
            .||.::...||:..:..     ......:...|                 |:.:|:  .|..|:.
Zfish   247 LSDLSLTADGFIGHYRFKWRSPSTASAPLTPAGTISPSTPPAALTYSEELCKQKCKRTGTIESHY 311

  Fly   777 CS 778
            ||
Zfish   312 CS 313

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tldNP_524487.2 ZnMc_BMP1_TLD 137..338 CDD:239808
Astacin 144..339 CDD:279708
CUB 388..474 CDD:214483
CUB 478..586 CDD:278839 43/108 (40%)
FXa_inhibition 595..630 CDD:291342 7/34 (21%)
CUB 634..750 CDD:278839 38/116 (33%)
FXa_inhibition 757..792 CDD:291342 7/41 (17%)
CUB 797..906 CDD:278839
CUB 910..1023 CDD:278839
pcolce2aXP_009295891.1 CUB 29..139 CDD:238001 50/145 (34%)
CUB 150..263 CDD:238001 38/118 (32%)
NTR_PCOLCE 292..415 CDD:239631 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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