DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and c6ast4

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	NP_001020351.1	Gene:	c6ast4 / 574001	ZFINID:	ZDB-GENE-050626-100	Length:	265	Species:	Danio rerio

Alignment Length:	263	Identity:	86/263 - (32%)
Similarity:	126/263 - (47%)	Gaps:	45/263 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 SQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAV------------TAKKER----------IW- 529
            |.:|::...|......||.|..|  |.||..|.:            .|..||          :|
Zfish    18 SVRAEEMMQPAAVDESAELSVSE--LLHRANRGIIPEADEPKLLDDIAVNERNADPCTSYSCLWP 80

  Fly   530 DYG----VIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPNYIVFTVRSCGCCSFV 590
            .|.    .:||.|..::|.....:.:..:..:.:.:||:|..|..|  .:||....|| ||.|:|
Zfish    81 KYSDGKIYVPYVIANHYSSRELEIIQRGLDSFASVSCIRFFRRSNE--RDYISIESRS-GCYSYV 142

  Fly   591 GKRGNGPQAISIGRN-CDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNMLS 654
            |::|| .|.:|:.|: |.....|.|||.|.:||.||.||.||:.|:.:...||:....||||
Zfish   143 GRQGN-VQTVSLARSGCLYHSTVQHELLHALGFNHEQTRSDRDNHIQVIWENILDDMKYNFN--- 203

  Fly   655 PDEVDSL--GMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLL 717
              ::::|  |..|||.|:|.|.|..|||..| .|::||.   ....|:|:..::||.||.:.|.|
Zfish   204 --KINTLNQGTPYDYKSVMQYERYAFSKNGY-PTMIPIP---NNNAELGKSTQMSQNDITRLNRL 262

  Fly   718 YKC 720
            |:|
Zfish   263 YQC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	75/231 (32%)
		Astacin	527..721	CDD:279708	73/212 (34%)
		CUB	723..836	CDD:294042
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
c6ast4	NP_001020351.1	Astacin	78..265	CDD:279708	71/199 (36%)
c6ast4	NP_001020351.1	ZnMc	84..265	CDD:294052	69/193 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810