DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and he1.1

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	NP_001038639.1	Gene:	he1.1 / 569018	ZFINID:	ZDB-GENE-021211-3	Length:	263	Species:	Danio rerio

Alignment Length:	188	Identity:	72/188 - (38%)
Similarity:	103/188 - (54%)	Gaps:	11/188 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   534 IPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQ 598
            :||.:.|.||...|::...|:..:...|||:||.|  .|..:|:....:. ||.|.:|:.| |.|
Zfish    86 VPYVVSGEFSINDKSVIANAISIFHAQTCIRFVPR--SIQADYLSIENKD-GCYSAIGRTG-GKQ 146

  Fly   599 AISIGR-NCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNMLSPDEVDSLG 662
            .:|:.| .|...||..|||.|.:||:||.:|.||:::|.|..|||..|..|||   ...:.::..
Zfish   147 VVSLNRKGCVYSGIAQHELNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNF---LKQKTNNQN 208

  Fly   663 MAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKC 720
            ..|||.|:|||.:..|:....|:||.||.   .:..:||||..||:.||.:.|.||.|
Zfish   209 TPYDYGSLMHYGKTAFAIQPGLETITPIP---DENVQIGQRQGLSKIDILRINKLYGC 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	72/188 (38%)
		Astacin	527..721	CDD:279708	72/188 (38%)
		CUB	723..836	CDD:294042
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
he1.1	NP_001038639.1	ZnMc_hatching_enzyme	81..263	CDD:239810	71/186 (38%)
he1.1	NP_001038639.1	Astacin	86..263	CDD:279708	71/186 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810