DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and CG10280

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	NP_001246942.1	Gene:	CG10280 / 40740	FlyBaseID:	FBgn0037395	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	76/245 - (31%)
Similarity:	116/245 - (47%)	Gaps:	46/245 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   512 PLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPNY 576
            |:||         .:|:|..|.||:||...::...:.....|::.:.:.||:.||..|.|: .:|
  Fly   141 PMRH---------PKRLWPNGTIPFEISPRYANQERQAIIQAVKTFNSLTCVHFVPYDGEV-DDY 195

  Fly   577 IVF---TVRSCGCCSFVGKRGNGPQAISIGR------NC-DKFGIVVHELGHVVGFWHEHTRPDR 631
            ::.   .....||.|:||:|| |.|.:|:.|      :| ...|.::|||.|.:|.:||.:|.||
  Fly   196 LLIEPPLEGPQGCWSYVGRRG-GEQVVSLQRPDENSAHCFSSEGRIMHELMHAIGIYHEQSRADR 259

  Fly   632 EKHVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRK 696
            :..|.|..:||:.....||.::|..: ......|||:|:|||....|||           .||.|
  Fly   260 DNFVKIHWDNIVPRFRKNFKLVSKKK-GKYAFDYDYNSVMHYGEFYFSK-----------RKGEK 312

  Fly   697 ------RP--EIGQRLRLSQGDIAQANLLYKC-----PKCGRTFQESSGI 733
                  :|  .||||..:|:.|..:.|.||.|     .|..|:|....|:
  Fly   313 PTMTPLQPGVRIGQRKTISKIDCLKINELYGCLQGRRAKMYRSFCHLLGL 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	69/223 (31%)
		Astacin	527..721	CDD:279708	69/216 (32%)
		CUB	723..836	CDD:294042	3/11 (27%)
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
CG10280	NP_001246942.1	Astacin	147..344	CDD:279708	68/210 (32%)
CG10280	NP_001246942.1	ZnMc_astacin_like	151..342	CDD:239807	64/204 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840