DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and Tnfaip6

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	NP_033424.1	Gene:	Tnfaip6 / 21930	MGIID:	1195266	Length:	275	Species:	Mus musculus

Alignment Length:	125	Identity:	44/125 - (35%)
Similarity:	64/125 - (51%)	Gaps:	8/125 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1267 HSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFD 1331
            |:..|||..   :..::.:....|.| :|||...|.|.|.......:.|.||.||:|....|..|
Mouse   131 HAKECGGVF---TDPKRIFKSPGFPN-EYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLAD 191

  Fly  1332 YVQVFSDIDDVYGQYGPMYGQYCGNVLPQDINSMTHSLLVRFKTDGSVPMKGFSASYVAV 1391
            ||:::...|||:|    ..|:|||:.||:||.|..:.:.::|.:|.||...||...||.|
Mouse   192 YVEIYDSYDDVHG----FVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTV 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808
		Astacin	527..721	CDD:279708
		CUB	723..836	CDD:294042
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839	44/125 (35%)
		CUB	1271..1390	CDD:238001	41/118 (35%)
Tnfaip6	NP_033424.1	Link_domain_TSG_6_like	36..128	CDD:239592
		CUB	135..244	CDD:278839	40/116 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	253..275
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900