DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and Adgrg6

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	XP_006512741.1	Gene:	Adgrg6 / 215798	MGIID:	1916151	Length:	1258	Species:	Mus musculus

Alignment Length:	334	Identity:	80/334 - (23%)
Similarity:	135/334 - (40%)	Gaps:	100/334 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1153 CKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVA 1217
            |..|.|:..:|.|.||..||.||:.||....|.|......|:.|::.||:||:|....|.||:::
Mouse    46 CGCGSCRLVLSNPSGTFTSPCYPNDYPNTQSCSWTLRAPAGYIIQITFNDFDIEEAPNCIYDSLS 110

  Fly  1218 VYDGESESSSVLGRFCGDKIP-FPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLR----- 1276
            :.:|||::     :|||.... ...:|:.|:|::...:|.:.||.||.||       |:|
Mouse   111 LDNGESQT-----KFCGATAKGLSFNSSVNEMHVSFSSDFSIQKKGFNAS-------YIRVAVSL 163

  Fly  1277 ----------------------ATSQVQQF---YSHARFGNQDYDDGMDCEWT-IAAPDNSYVQL 1315
                                  :..:::.|   :..::.||:..|      || .:..|.|..||
Mouse   164 RNQKVILPQTLDAYQVSVAKSISIPELKAFTLCFEASKVGNEGGD------WTAFSYSDESLTQL 222

  Fly  1316 IFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYC--GNVLP----QDI--NSMTHSLLVR 1372
            :    .:|.:.|                |.:..:.|..|  .|.||    :||  .::....||.
Mouse   223 L----SLEKASN----------------GYFLSISGSRCLLNNALPVKDKEDIFTENLEQLCLVW 267

  Fly  1373 FKTDGSVPMKGFSASYVAVPNSGEYDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQEETDEYSD 1437
            ..:.||:.: .|..:|..||           .:::.|:  |.|..|:|.      ...:.||.:.
Mouse   268 NNSWGSIGI-NFKKNYETVP-----------CDSTISA--VVPGDGTLL------LGSDRDEVAS 312

  Fly  1438 FSGNQLVFN 1446
            ..|:  ::|
Mouse   313 LRGS--IYN 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808
		Astacin	527..721	CDD:279708
		CUB	723..836	CDD:294042
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342	80/334 (24%)
		CUB	1158..1267	CDD:278839	38/109 (35%)
		CUB	1271..1390	CDD:238001	28/157 (18%)
Adgrg6	XP_006512741.1	CUB	48..156	CDD:238001	40/119 (34%)
		LamG	188..347	CDD:389952	37/180 (21%)
		HRM	543..588	CDD:382965
		GPS	809..854	CDD:366827
		7tm_GPCRs	869..1137	CDD:391938
		TM helix 1	871..896	CDD:341315
		TM helix 2	906..928	CDD:341315
		TM helix 3	939..966	CDD:341315
		TM helix 4	981..997	CDD:341315
		TM helix 5	1026..1049	CDD:341315
		TM helix 6	1072..1097	CDD:341315
		TM helix 7	1101..1126	CDD:341315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810