DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tok and nas-30

DIOPT Version :9

Sequence 1:NP_001287510.1 Gene:tok / 42944 FlyBaseID:FBgn0004885 Length:1464 Species:Drosophila melanogaster
Sequence 2:NP_490795.5 Gene:nas-30 / 190803 WormBaseID:WBGene00003548 Length:741 Species:Caenorhabditis elegans


Alignment Length:414 Identity:121/414 - (29%)
Similarity:183/414 - (44%) Gaps:68/414 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   495 SVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWEN 559
            :|.:|..:.....:...|...:..:.:|....| |. .|||:...|. ....|.|.:..:..||.
 Worm   300 TVKQMKAIVLAAQEARNPHGRKKRKVITGSVYR-WK-SVIPFRFKGG-DAKWKKLIREGLGLWEK 361

  Fly   560 STCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWH 624
            .||:::.|..|  ..:|::| .|..||.|.||:.| |.|.||||..|:..|||.||:||.:||||
 Worm   362 ETCVRWSENGP--GKDYVIF-FRGSGCYSSVGRTG-GSQLISIGYGCEDKGIVAHEVGHSLGFWH 422

  Fly   625 EHTRPDREKHVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILP 689
            |.:||||:.::.:..:.|:||.|.||...|.:|::.:|:.||..|:|||..|.|:|.  .|.| .
 Worm   423 EQSRPDRDDYIHLRKDWIIKGTDGNFEKRSWEEIEDMGVPYDVGSVMHYGSNAFTKD--WDQI-T 484

  Fly   690 IEMK-GRKRPEIGQRLRLSQGDIAQANLLY-------------------------KCPK------ 722
            ||.| .|.:..||||.:||..|:.|.|.||                         |||.      
 Worm   485 IETKDSRYQGTIGQRQKLSFIDVKQVNRLYCNSVCPVALPCMHGGYPDPNNCAVCKCPDGLGGKL 549

  Fly   723 CGR----TFQESSGIFASPSHYTAGALSNETEH-----CEWRITATYGERVELKLENMNIFKSNN 778
            |||    |..:..|     ...||.|...|..:     |.|::.:..|.||.|.|..:....:..
 Worm   550 CGRAAKGTDHDKCG-----GELTATAEWQEMVYKGKRTCNWKVKSPSGGRVRLVLTELRYQCAPA 609

  Fly   779 CETDYLEIRDGYFEKSPLIGRFCGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVVCGGE 843
            |:. |:||:.....:.......|.....:||..:|..::|:  |.:.::....:|.::       
 Worm   610 CKA-YIEIKHNTDFQQTGFRVCCFNKTYDVISDQSEALILS--NANIVDYEVSYKLQW------- 664

  Fly   844 LSVDDAVGRLESPNYPLDYLPNKE 867
              :.|....|..|.....::|.||
 Worm   665 --IQDNGKALPPPKPTSTWVPGKE 686

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tokNP_001287510.1 ZnMc_BMP1_TLD 520..721 CDD:239808 83/226 (37%)
Astacin 527..721 CDD:279708 82/219 (37%)
CUB 723..836 CDD:294042 27/121 (22%)
CUB 840..951 CDD:278839 6/28 (21%)
FXa_inhibition 958..993 CDD:291342
CUB 997..1111 CDD:278839
FXa_inhibition 1118..1153 CDD:291342
CUB 1158..1267 CDD:278839
CUB 1271..1390 CDD:238001
nas-30NP_490795.5 ZnMc_astacin_like 336..514 CDD:239807 77/185 (42%)
CUB 564..648 CDD:412131 19/84 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.