DRSC/TRiP Functional Genomics Resources

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Protein Alignment tok and clec-12

DIOPT Version :10

Sequence 1:NP_476879.1 Gene:tok / 42944 FlyBaseID:FBgn0004885 Length:1464 Species:Drosophila melanogaster
Sequence 2:NP_493166.1 Gene:clec-12 / 189004 WormBaseID:WBGene00012103 Length:421 Species:Caenorhabditis elegans


Alignment Length:428 Identity:101/428 - (23%)
Similarity:145/428 - (33%) Gaps:147/428 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   907 GQDAPLI--GVFCGYKPPPNM----KSSGNSMYVKFVSDTSVQKAGFSAVFMKEV---------- 955
            |...|||  |::|....|...    .|...|.|..|       .|||..|.:.:.          
 Worm    78 GSSTPLIWLGLYCFDSDPAQCLWDDVSGSASNYNNF-------SAGFPLVVLGQCVYYSTQGALA 135

  Fly   956 -----DECETQNHGCEHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNG---TITSPS 1012
                 :|||:|:           ..|.|...|.:..:.|..:            ||   |.:|.:
 Worm   136 GKWLSEECESQH-----------VAYICELPITYTDNCDFNY------------NGYCYTFSSTT 177

  Fly  1013 FPEMYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFC 1077
                                  .|:| |....:||..|  |||| ..:::|.|   .::.|.||.
 Worm   178 ----------------------NSIN-TFISAQGTCAQ--DCGY-LASIHSPL---EIRYINTFA 213

  Fly  1078 --------------GS------------SIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDID 1116
                          ||            :|.|..|:     |:::....|....|.:...|....
 Worm   214 PHAYFYIGAIWKNDGSLYWLDNSPWDYNNIDPVQTN-----RVDYCLTMSTTNFGSSPAGFWFST 273

  Fly  1117 ECAVNNGGCQHECRNTIGSYICMCHNGYSMH-----------ENGHDCKEGECKYEISAPFGTIF 1170
            .|            |..|.|||....|....           .|..:|..|....:     |.|.
 Worm   274 NC------------NNPGYYICKRQAGVQCSAAPPATVTPSPANPSNCNAGRLMSD-----GIIT 321

  Fly  1171 SPNYPDSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGD 1235
            |||:|.:|..||:|.:...|....||.|.|..|:.:     .||.|.:||||:.||.|||::.|:
 Worm   322 SPNFPQNYFNNANCAYQISTLGSMRIALTFTFFNTQ-----PYDLVTIYDGETSSSPVLGKYGGN 381

  Fly  1236 KIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGG 1273
            :.....:|:.|.|.:...||.....|||:|..|:...|
 Worm   382 QSSLTFTSSRNNMLVTFITDGKDTSNGFSARFSSIVYG 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tokNP_476879.1 ZnMc_BMP1_TLD 520..721 CDD:239808
CUB 723..836 CDD:412131
CUB 840..951 CDD:395345 14/49 (29%)
FXa_inhibition 958..993 CDD:464251 7/34 (21%)
CUB 997..1111 CDD:395345 27/142 (19%)
FXa_inhibition 1118..1153 CDD:464251 8/45 (18%)
CUB 1158..1267 CDD:395345 38/108 (35%)
CUB 1271..1390 CDD:238001 1/3 (33%)
clec-12NP_493166.1 CLECT 26..153 CDD:214480 20/92 (22%)
CLECT 166..284 CDD:214480 33/175 (19%)
CUB 313..415 CDD:238001 38/111 (34%)
Blue background indicates that the domain is not in the aligned region.

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