DRSC/TRiP Functional Genomics Resources

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Protein Alignment tok and nas-20

DIOPT Version :9

Sequence 1:NP_001287510.1 Gene:tok / 42944 FlyBaseID:FBgn0004885 Length:1464 Species:Drosophila melanogaster
Sequence 2:NP_505906.2 Gene:nas-20 / 188420 WormBaseID:WBGene00003539 Length:379 Species:Caenorhabditis elegans


Alignment Length:353 Identity:81/353 - (22%)
Similarity:143/353 - (40%) Gaps:100/353 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   524 KKERIWDYGV------------IPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPN- 575
            |::.:.||..            :|.|:        :|:|:.|:.:.||.||:||     |.:.| 
 Worm    28 KRQAMRDYAKWENNKMSLFFYNLPLEM--------QAMFRDAINYLENHTCLKF-----EYNENA 79

  Fly   576 -YIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEH 639
             ..|...:..||.|..|......|.:::..||..||..|||:.|.:|..|...|.||:.:::::.
 Worm    80 ETAVRIRKGNGCYSLYGMHAGEVQDLTLDYNCASFGTAVHEIMHALGIAHGQARSDRDDYLIVDS 144

  Fly   640 NNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPE----I 700
            .|...|.:...|:          :.:||.|:|.|||:..|     |..:||:      ||    :
 Worm   145 TNSNDGIENTENL----------VPFDYGSVMLYARDPHS-----DKRIPID------PEYNFTM 188

  Fly   701 GQRLRLSQGDIAQANLLY----------------------KCPKC-------GRTFQESSGIFA- 735
            |. ||::..|:...|..|                      .|.:|       |:...:..|::. 
 Worm   189 GS-LRVAFYDMVLLNKFYGCNCDNHPRKLDCKNGGYQNPANCEECLCTDGFNGQLCDQHEGVYVL 252

  Fly   736 -SPSHYTAGALSN------ET----EHCEWRITATYGERVELKLENMN-IFKSNNCETDYLEIRD 788
             :...:.|..:.|      ||    |:..:.:||..|..:|:::..:: .|..:.|:.:.:|::.
 Worm   253 EAKKEWDASGVRNNYRKGIETNTMPEYTYFALTAPEGSTIEVRITKLSGFFCQHTCDYNGVELKY 317

  Fly   789 GYFEK--SPLIGRFCGKVDKEVIRTESS 814
            ....:  |||:   |...|....:|.||
 Worm   318 KTDRRIVSPLV---CCDNDNLWNKTRSS 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tokNP_001287510.1 ZnMc_BMP1_TLD 520..721 CDD:239808 57/236 (24%)
Astacin 527..721 CDD:279708 56/233 (24%)
CUB 723..836 CDD:294042 23/114 (20%)
CUB 840..951 CDD:278839
FXa_inhibition 958..993 CDD:291342
CUB 997..1111 CDD:278839
FXa_inhibition 1118..1153 CDD:291342
CUB 1158..1267 CDD:278839
CUB 1271..1390 CDD:238001
nas-20NP_505906.2 Astacin 36..209 CDD:279708 54/207 (26%)
ZnMc 49..205 CDD:294052 53/190 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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