DRSC/TRiP Functional Genomics Resources

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Protein Alignment tok and clec-20

DIOPT Version :10

Sequence 1:NP_476879.1 Gene:tok / 42944 FlyBaseID:FBgn0004885 Length:1464 Species:Drosophila melanogaster
Sequence 2:NP_494003.1 Gene:clec-20 / 188251 WormBaseID:WBGene00020328 Length:417 Species:Caenorhabditis elegans


Alignment Length:460 Identity:79/460 - (17%)
Similarity:149/460 - (32%) Gaps:158/460 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   898 DYVEVRDGPGQDAPL-IGVFC---------------------GYKPPPNMKSSGNSMYVKFVSD- 939
            ::::|....|:|..: :|::|                     |::..||: :.||.:.|...|: 
 Worm    66 EHIDVTTLSGKDKNVWLGLYCINNYRSNCLWDDSNISTDQRNGFQSRPNV-TQGNCVTVNTTSEH 129

  Fly   940 -TSVQKAGFSAVFMKEVDECE---TQNHGCEHECINTLGGYECSCRIGFELHS---DKKHCEDAC 997
             :|...:..|.:|:     ||   |....|:|       .|..||.|.....|   .::.||:.|
 Worm   130 WSSTDCSKESNLFV-----CELPTTFEDNCQH-------NYNGSCYIPHVASSFIRAQRTCEEEC 182

  Fly   998 GGVIEYPNG------TITSPSFPEMYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHQQSDCGY 1056
            |.::...:.      .|.:.:|.:...:....:|.:...|.......:.|..::....::..|  
 Worm   183 GSLVSIHSANENRYFNILASTFAQNEQVFIGGMWTLSGRPSWIDGSRWDHDKIDSLRKREGAC-- 245

  Fly  1057 DSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDIDECAVN 1121
                                                 |....:||.:|..: .:::|        
 Worm   246 -------------------------------------LVVSGEKSNERQPW-GLWYT-------- 264

  Fly  1122 NGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGE-----------CKYEISAPFGTIFSPNYP 1175
             |.|.::.:     :.|       ....|..|....           |...|....|.|.:|...
 Worm   265 -GNCDYDRK-----FFC-------KRPAGEKCNPDRPEDPTPPVLYTCNTTILVTQGLIIAPPIT 316

  Fly  1176 DSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFP 1240
            ::...:..|.:|..|.....|.|.|.:.|:..:    |..:..|||:||:|.::........| .
 Worm   317 EAGLEHGFCYYHIYTVGSSSIMLTFTQLDMHPN----YHELNAYDGDSENSRLISTIHNYNSP-T 376

  Fly  1241 ISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTI 1305
            ::|:.|.|::..::      ||                :....|..||||          .|:..
 Worm   377 LTSSGNAMFVTFRS------NG----------------TSTNWFGFHARF----------TEFYF 409

  Fly  1306 AAPDN 1310
            |:|.|
 Worm   410 ASPMN 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tokNP_476879.1 ZnMc_BMP1_TLD 520..721 CDD:239808
CUB 723..836 CDD:412131
CUB 840..951 CDD:395345 14/76 (18%)
FXa_inhibition 958..993 CDD:464251 10/40 (25%)
CUB 997..1111 CDD:395345 12/119 (10%)
FXa_inhibition 1118..1153 CDD:464251 4/34 (12%)
CUB 1158..1267 CDD:395345 25/108 (23%)
CUB 1271..1390 CDD:238001 9/40 (23%)
clec-20NP_494003.1 CLECT 23..145 CDD:214480 15/84 (18%)
CLECT 158..276 CDD:214480 23/178 (13%)
CUB 299..405 CDD:238001 30/142 (21%)
Blue background indicates that the domain is not in the aligned region.

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