Protein Alignment tok and nas-29

DIOPT Version :9

• Sequence 1: NP_001287510.1
• Gene: tok / 42944
• FlyBaseID: FBgn0004885
• Length: 1464
• Species: Drosophila melanogaster
• Sequence 2: NP_494953.3
• Gene: nas-29 / 186488
• WormBaseID: WBGene00003547
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 125/630 - (19%)
• Similarity: 224/630 - (35%)
• Gaps: 190/630 - (30%)

  Fly   407 KQRRSNQHL-----------EHEVKLQRLREELSRPVIEAHHHQSHHQKQAQHRQHHQSHHRKKH 460
            :::.|:.||           |..:.:.:|.::....:.|.....|:  ||.....:..:.:||..
 Worm    53 EEQYSDSHLSFDVSTIYNYSEKPISIGKLNKKYRDILFEGDMAISY--KQLSMIVNGSTEYRKAI 115

  Fly   461 RRQQQHHRRRGQSTTQ-----YVNHSPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARA 520
            :.:::.::..|:||.:     |::::.|.
 Worm   116 KSRRRGNKINGESTDRTKRQAYLDNNYPA------------------------------------ 144

  Fly   521 VTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHP-----NYIVFT 580
                  .||..|| .:....:.:.|.|.....|:..|...|||:|       ||     .|::|.
 Worm   145 ------TIWKNGV-AFMFHESLTPIAKTAILKAVHFWYRETCIEF-------HPRTFQKEYLLFI 195

  Fly   581 VRSCGCCSFVGK-RGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMK 644
            ....||.|.||: ...|.|.:|||..|:.||:..|||.|.:|.:||.:|.||::.||.....:.:
 Worm   196 GNDDGCWSTVGRDASQGKQVVSIGNGCEHFGVTSHELAHALGIFHEQSRFDRDESVVFNPRVVER 260

  Fly   645 GQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQG 709
            ...:||..:||.::.:.|:.||..|:|||....||....:.|:..|:
 Worm   261 DLLFNFAKISPRQMSTYGLPYDIGSVMHYTPTEFSNIPSIPTLAAID------------------ 307

  Fly   710 DIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVELKLENMNIF 774
                .||           |::.|....|| :....:.|:...|:.:..      .:...:|....
 Worm   308 ----TNL-----------QQTMGQLEGPS-FVDVHIMNQHYQCQEKCP------TQAPCQNGGFT 350

  Fly   775 KSNNCETDYLEIRDGYFEKSPLIGRFCGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVV 839
            .|.||:........|        |.:|..:                            .:.|...
 Worm   351 NSRNCKVCKCPTGFG--------GAYCQLI----------------------------ASSFSPF 379

  Fly   840 CGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQVALKFQSFEVENHDSCVYDYVEVRD 904
            |||.|:.::...|.:..........:|.||:.|..||..::.:.....:.:..:.|..|.:|::
 Worm   380 CGGYLNAEETTRRFDITIRQSTTTRSKTCVYHIKAPEGKRIIIDILKIDSKCIEGCWQDGLELK- 443

  Fly   905 GPGQDAPLIGV-FCGYKPPPNMK---SSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECETQNHGC 965
             ..:|...:|. ||  .|..:.:   |.||  .|.|:            ||.||.|    .:...
 Worm   444 -MKKDFRPVGYRFC--CPESSRRKVISEGN--MVPFM------------VFSKEHD----FSVSF 487

  Fly   966 EHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNGTITS 1010
            |:..::|..|::           |:|:..|.   :::..:|...|
 Worm   488 EYSFVSTSAGFD-----------DEKNDSDV---IVDNLDGVFVS 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	58/206 (28%)
		Astacin	527..721	CDD:279708	58/199 (29%)
		CUB	723..836	CDD:294042	13/112 (12%)
		CUB	840..951	CDD:278839	24/114 (21%)
		FXa_inhibition	958..993	CDD:291342	5/34 (15%)
		CUB	997..1111	CDD:278839	2/14 (14%)
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
nas-29	NP_494953.3	Astacin	145..336	CDD:279708	64/232 (28%)
		ZnMc_astacin_like	148..332	CDD:239807	61/225 (27%)
		CUB	404..491	CDD:214483	25/108 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810