DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tok and nas-9

DIOPT Version :9

Sequence 1:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster
Sequence 2:	NP_741532.1	Gene:	nas-9 / 178875	WormBaseID:	WBGene00003528	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	72/251 - (28%)
Similarity:	113/251 - (45%)	Gaps:	32/251 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 WD-YGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKF-VERDPE-IHPNYI-VFTVRSCGCCSF 589
            || :..|.|.:|.:.....|...:.|:.....:|||.| ....|: .|.||: |.:...|| .|:
Worm   313 WDIWKPIQYTLDDSLEESDKKDIRDALHEISINTCILFRYNATPKGYHLNYMKVDSTTFCG-LSY 376

  Fly   590 VGKRGNGPQAISIGRNC-DKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNML 653
            || |.:....|.:...| |..|:.:||..|.:|..|:|.|.||:|::.|:.:|| ..|.|:...:
Worm   377 VG-RTDPANPIYLSFQCGDNRGVAMHETMHALGVSHQHLRLDRDKYIKIDWSNI-DPQHYDTFAI 439

  Fly   654 SPDEV-DSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLL 717
            |..:: .|.|..|.|||||||.....:|.....|::|:.......|::|||.:|::|||.....:
Worm   440 SDAKLYTSYGTKYAYDSIMHYNAYLGAKDPNKPTMIPLVNPQENTPKLGQRAKLTRGDIRLLKKM 504

  Fly   718 YKCPKCGRTFQESSGIFASPSHYTAGALSNETEHC-EWRITATYGERVELKLENMN 772
            |..|.|                      .::..|| .|.:......:.::|..|.|
Worm   505 YCRPGC----------------------DDQNVHCGTWALHGYCKMKEQMKWMNEN 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	64/197 (32%)
		Astacin	527..721	CDD:279708	64/197 (32%)
		CUB	723..836	CDD:294042	7/51 (14%)
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
nas-9	NP_741532.1	Astacin	311..505	CDD:279708	63/194 (32%)
		ZnMc_astacin_like	316..505	CDD:239807	61/191 (32%)
		ShKT	510..546	CDD:214586	7/51 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910