DRSC/TRiP Functional Genomics Resources

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Protein Alignment tok and clec-5

DIOPT Version :10

Sequence 1:NP_476879.1 Gene:tok / 42944 FlyBaseID:FBgn0004885 Length:1464 Species:Drosophila melanogaster
Sequence 2:NP_498022.1 Gene:clec-5 / 175652 WormBaseID:WBGene00016450 Length:419 Species:Caenorhabditis elegans


Alignment Length:403 Identity:92/403 - (22%)
Similarity:134/403 - (33%) Gaps:154/403 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   927 SSGNS-MYVKFVSDTSVQKAGFSAVFMKEVDEC---ETQ--------NHGCEHE----------- 968
            |:|:: ||..|.|       ||..|   ::.:|   .||        |..||.:           
 Worm   100 STGSAEMYNSFAS-------GFPLV---DIGKCVYYSTQGSLAGKWLNGNCESDPRAFVCELPAT 154

  Fly   969 -CINTLGGYECSCRIGFELHSDKKH-------CEDACGGVIEYPNGTITSPSFPEMYPLLKECIW 1025
             ..|....|...|   |.||:::..       ||..||.:                         
 Worm   155 HADNCTYNYNGHC---FTLHTERNTFVQAQAICEQECGNL------------------------- 191

  Fly  1026 EIVAPPKHRISLNFTHFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTAT---- 1086
                                .:.|..::..|.|..:.|.:   .|.....:.|:|.|.::.    
 Worm   192 --------------------ASIHSSNENRYLSSIMSSIM---NLSNSSVYIGASWPSSSVFNWL 233

  Fly  1087 SESNALRLEFHSDKSIQRSGFAAVFFTDIDECAVNNGGC-----------------QHECRNTIG 1134
            ..||       ||            :|:||:...:.|.|                 ...|...: 
 Worm   234 DGSN-------SD------------YTNIDQSFGHGGNCALLSNYQPSVVPMGYWFSFPCTAAV- 278

  Fly  1135 SYICMCHNGYS------------MHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWH 1187
            .:||....|..            :..|...|.    ...:.|| |.|.|||||.:|..|..|.:|
 Worm   279 PFICKRSAGIKCSGTPPPVTVTPVPSNPSFCN----STLLIAP-GVITSPNYPSNYDNNQFCSYH 338

  Fly  1188 FITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVL 1252
            ..|...:|:.|.|:.|..    |..:|.|.||:|||.|||.:||:.|...||.:.||.|.|::..
 Worm   339 LSTLGSYRVLLHFSAFAT----EVNFDLVVVYNGESASSSQIGRYSGSLDPFSVVSTGNNMFVTF 399

  Fly  1253 KTDKNKQKNGFTA 1265
            |||.:....||:|
 Worm   400 KTDGSGVAQGFSA 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tokNP_476879.1 ZnMc_BMP1_TLD 520..721 CDD:239808
CUB 723..836 CDD:412131
CUB 840..951 CDD:395345 8/24 (33%)
FXa_inhibition 958..993 CDD:464251 12/64 (19%)
CUB 997..1111 CDD:395345 14/117 (12%)
FXa_inhibition 1118..1153 CDD:464251 7/63 (11%)
CUB 1158..1267 CDD:395345 44/108 (41%)
CUB 1271..1390 CDD:238001
clec-5NP_498022.1 CLECT 23..150 CDD:214480 15/59 (25%)
CLECT 163..283 CDD:214480 28/190 (15%)
CUB 309..416 CDD:238001 45/113 (40%)
Blue background indicates that the domain is not in the aligned region.

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