| Sequence 1: | NP_001262924.1 | Gene: | slo / 42940 | FlyBaseID: | FBgn0003429 | Length: | 1217 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001027006.2 | Gene: | KCNU1 / 157855 | HGNCID: | 18867 | Length: | 1149 | Species: | Homo sapiens |
| Alignment Length: | 1180 | Identity: | 438/1180 - (37%) |
|---|---|---|---|
| Similarity: | 625/1180 - (52%) | Gaps: | 202/1180 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 35 FLLSSIFTFLAGLLVVLLWRAFAFVCCRKEPDLGPNDPKQKEQKASRNKQEFEGT---------- 89
Fly 90 -----------FMTEAKDWAGELISGQTTTGRILVVLVFILSIASLIIYFVDASSEEVERCQKWS 143
Fly 144 NNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLR 208
Fly 209 ALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDP-LDFNNAHRLSYW 272
Fly 273 TCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAVFASWIPEITELAAQRSKYGGTYSKDP 337
Fly 338 RKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKEPDLELEGLLKRHYTTVAFFQGTM 402
Fly 403 MNAVDLERVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLL 467
Fly 468 NIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGC 532
Fly 533 EMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGA-EEGADSKISINPRGAKIQANTQGFF 596
Fly 597 IAQSADEVKRAWFYCKACHEDIKDETLIKKCKCKNYVGMIMMQTGMVNQGITSVMNTMEDEHHPA 661
Fly 662 PTFTPPELPKRVHVRGSVSGDITRDREDTNLLNRNVRRPNGTGNGTGGMHHMNNTAAAAAAAAAA 726
Fly 727 GKQVNKVKPTV-NVSRQVEGQVISPSQYNRPPENDANPYAGYQLAYEVKKLMPTSRSSGTGTQNQ 790
Fly 791 NGGVSLPAGIADDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLF 855
Fly 856 ADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADL 920
Fly 921 RAVNVNLCDMCCILSAKVPSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAG 985
Fly 986 SPIVLQRR-GSVYGAN-------VPMITELVNDSNVQFLDQ---DDDDDPDTELYLTQPFACGTA 1039
Fly 1040 FAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQ 1104
Fly 1105 ISLYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLP 1169
Fly 1170 TDQVFVLMQF 1179 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| slo | NP_001262924.1 | Ion_trans | 110..321 | CDD:395416 | 115/211 (55%) |
| BK_channel_a | 470..566 | CDD:397526 | 45/95 (47%) | ||
| KCNU1 | NP_001027006.2 | Ion_trans | 141..323 | CDD:278921 | 102/181 (56%) |
| Ion_trans_2 | 230..317 | CDD:285168 | 46/86 (53%) | ||
| Selectivity for potassium | 276..279 | 2/2 (100%) | |||
| BK_channel_a | 469..557 | CDD:281490 | 41/88 (47%) | ||
| Segment S7 | 480..500 | 11/19 (58%) | |||
| Segment S8 | 537..557 | 10/19 (53%) | |||
| Segment S9 | 711..731 | 6/19 (32%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 828..854 | 8/41 (20%) | |||
| Segment S10 | 895..915 | 10/19 (53%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1118..1149 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1420 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG53496 | |
| OrthoDB | 1 | 1.010 | - | - | D41052at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003516 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_101271 | |
| Panther | 1 | 1.100 | - | - | O | PTHR10027 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.790 | |||||