Protein Alignment puf and UBP15

DIOPT Version :9

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_014033.1
• Gene: UBP15 / 855350
• SGDID: S000004920
• Length: 1230
• Species: Saccharomyces cerevisiae
• Alignment Length: 1071
• Identity: 218/1071 - (20%)
• Similarity: 371/1071 - (34%)
• Gaps: 327/1071 - (30%)

  Fly  2000 WDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLRVPPNAARKHGPTLLELQRM 2064
            |..:...:.:...||||..|.|||||:.|.:|..:.....|..|..:|......:....|.|||.
Yeast   190 WHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRA 254

  Fly  2065 FAYLLESERKSYNPRSFCRVYQMDHQPLNTGE--------------QKDMAEFFIDLVSKLEDM- 2114
            |..|                 |:...||:|.|              |.|:.|....|:.:||:.
Yeast   255 FYQL-----------------QVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNM 302

  Fly  2115 --TPDLKHLVKRLFCGSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRNLQESLDEVTVKDTLEG 2177
              || ::..:..:|.|.:.:.:..::..:.|...|||:.::..|.:.:|||||.|.....:.:.|
Yeast   303 KGTP-VEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNG 366

  Fly  2178 DNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMR--YTFNMVTMLKEKVNTHFSFPLRLNMCHYV 2240
            :|.|.....|.: .|:|...|:..|.:|.....|  |.||...|:  |||..:.||..:::..:|
Yeast   367 ENQYAAQDYGLQ-DAQKGVIFESFPPVLHLQLKRFEYDFNYDQMV--KVNDKYEFPETIDLSPFV 428

  Fly  2241 EKTLMPQQYKEERERRQKEKEGADGSGDGNDNEKAEATLDDDIEECYEYELVGVTVHTGTADGGH 2305
            :|.::    |:..:...|:|..                        |.|.|.||.||:|....||
Yeast   429 DKDVL----KKTLDSENKDKNP------------------------YVYNLHGVLVHSGDISTGH 465

  Fly  2306 YYSFIKERTKTSYHTHERWFLFNDAEVKPFDPSQIAAECFGGEM--TSKTYDSVTEKYLDFSFEK 2368
            ||:.||...:      ::|:.|:|..|......|:..|.||.:.  ..|.......:|.::..::
Yeast   466 YYTLIKPGVE------DQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQR 524

  Fly  2369 TNSAYMLFYERR--------------LPEH-LQRRHSELLVTPTPSPTVEE-------------- 2404
            ..|||||.|.|:              :|:| :.|...|:....|....:.|
Yeast   525 HTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKE 589

  Fly  2405 ---------------KSEAEE---------------PTKMETSSSEIKADVDVEVEVEEKDKEKP 2439
                           :..|||               .||:....:.||..:::..|.:.|..:..
Yeast   590 FIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMD 654

  Fly  2440 AQTDTESKET-PAKEEIADDKSKQDEPEEKKIEKQSREGEE---KSETDEKPTEMTTVS-----T 2495
            .:.::..:.| |...|..:...::...:|||...|::.|||   .:|.|:|.. :.|||     .
Yeast   655 YRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKAL-LETVSFLDLFI 718

  Fly  2496 EE--------EKQPTANCDNHQQ---------------------------NNNSNSKASNDQQPS 2525
            ||        .|...|:..:..|                           :|.||........|.
Yeast   719 EEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPH 783

  Fly  2526 TSK-------AAQKLQLFRPLLNKELEDWIWQDN------------------RQFLQDRNI---- 2561
            |.|       |..:||.... ::..:||.|..:.                  ::.:.|.:|
Yeast   784 TQKLLGFGHFAVNQLQQLSD-ISAIIEDSISSNEKLTFYEEVQPGTINEIYMKETIYDADIDTGD 847

  Fly  2562 ---FE-------------------HTYFNFM--------------WQICGHIPQSLISETDVTCM 2590
               ||                   ::|..:.              :.:...||:|.  |..::..
Yeast   848 IVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESF--EFWISAY 910

  Fly  2591 AAKLSVSFFIETFIHAKEKPTMVPWVEL-----------------LTKQFNASQ------EACEW 2632
            |....::..:..:.|.  ||..:..:.|                 |.|.||..|      |....
Yeast   911 APYDDLARMVSKYAHV--KPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSV 973

  Fly  2633 FLSHMSQ----EPYWPVQVLI--QC-----PNQMVRQMFQRLVIHVIQQLRASHAHLYLEVETDE 2686
            .|..:.:    :.||.....|  ||     .|......|...|.|.|.             .|||
Yeast   974 PLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIG-------------FTDE 1025

  Fly  2687 DDKELIGQASCVTRFIGSLISLLEHGARANLRHLSEYFGLLCEFSRMGDEEAMYLLRIGVLKSLV 2751
            :.:.::...:...:|.|.|      ..:...:.:|:: .||  |.|:..||:.....:..|:::
Yeast  1026 EKENILLWTNTNFQFQGLL------SDQNTFKDVSKH-SLL--FGRILPEESKLFKELNRLENV- 1080

  Fly  2752 DFYLGHKQTDSIDISSDNEDNSSEEALSVEKMRPASLDKMIALCASLVERSRGADFRLRLSPKDF 2816
                   ||.|::...|:| |:::        ||...::.:.:.   :|.|.....|:.:..:.|
Yeast  1081 -------QTSSLEDFMDDE-NATD--------RPMDDEQDLGMA---IEHSEDMKGRIVVVQQYF 1126

  Fly  2817 SAIAGGKGFPFLYQQIKDGINPHQTKHLIHA 2847
            ..:....|..||:..|.|...| :||..:||
Yeast  1127 KDLENRHGISFLFNLIPDETFP-KTKDRLHA 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	102/403 (25%)
		UCH	2014..2377	CDD:278850	99/383 (26%)
		DUF3517	2723..>2877	CDD:288853	29/125 (23%)
UBP15	NP_014033.1	COG5077	1..1229	CDD:227409	218/1071 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810