Protein Alignment puf and Usp48

DIOPT Version :9

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: XP_006239296.1
• Gene: Usp48 / 362636
• RGDID: 735213
• Length: 1064
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 149/615 - (24%)
• Similarity: 238/615 - (38%)
• Gaps: 173/615 - (28%)

  Fly  1948 ADRQKPKCKSASSRASAYDLLVELC------RGCATNYAYLHGRLLAQHKSGPKQPYPWDYW--- 2003
            |:..:|:..|.....:||.:.:|.|      |.|..|...|.|  :.:|           .|
  Rat    43 AETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCRGNPNCLVG--IGEH-----------IWLGE 94

  Fly  2004 -----------PRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLRVPPNAA------ 2051
                       |..|.|.:..:|||||||||||:.:.:|..::..:.|.|:...|...:
  Rat    95 IDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGD 159

  Fly  2052 -----RKHGP-TLLE-LQRMFAYLLESERKSYNPRSFCRVYQMDHQPLNTGEQKDMAEFFIDLVS 2109
                 :.:.| |:.| ||.:||.|..|.|:..:|..|.:...:|     ||:|:|..||....:|
  Rat   160 GIRGGKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLD-----TGQQQDAQEFSKLFMS 219

  Fly  2110 KLED-----MTPDLKHLVKRLFCGSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRNLQESLDEV 2169
            .|||     ..||::::|::.|||..:...|...||..|:....||.:...:...:.|.:.:.|.
  Rat   220 LLEDTLSKQKNPDVRNVVQQQFCGEYAYVTVCSQCGRESKLVSKFYELELNIQGHKQLTDCISEF 284

  Fly  2170 TVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMRYTFNMVTMLKEKVNTHFSFPLRL 2234
            ..::.|||||.|.|..|..|..|.::.....||..|....||:.|:..|..|:|:|.:..|...|
  Rat   285 LKEERLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESL 349

  Fly  2235 NMCHYVEKTLMPQQYKEERERRQKEKEGADGSGDGNDNEKAEATLDDDIEECYEYELVGVTVHTG 2299
            :|..|||                 .|.|:                       :.|||..|.:|.|
  Rat   350 DMEPYVE-----------------HKGGS-----------------------FVYELSAVLIHRG 374

  Fly  2300 -TADGGHYYSFIKERTKTSYHTHERWFLFNDAEVKPFDPS--QIAAECFGGEMTSKTYDSVTEKY 2361
             :|..|||.:.:|:.....      |:.|||.:::..:..  |:..|    |..::...|.|.|
  Rat   375 VSAYSGHYIAHVKDPQSGD------WYKFNDEDIEKMEGKKLQLGIE----EDLAEPSKSQTRK- 428

  Fly  2362 LDFSFEK-------TNSAYMLFYERRLPEHLQRRHSELLVTPTPSPTVEEKSEAEEPTKMETSSS 2419
                 .|       :.:||||.|..:..|   :.|:.:.|                |..::
  Rat   429 -----PKCGKGTHCSRNAYMLVYRLQTQE---KNHTMVQV----------------PAFLQ---- 465

  Fly  2420 EIKADVDVEVEVEEKDKEKPAQTDTESKETPAKEEIADDKSKQDEPEEKKIEKQSREGEEKSETD 2484
                      |:.::|..|..:...|..|. .::.:  ||.:....|.|::.::...|.|
  Rat   466 ----------ELVDRDNSKFEEWCVEMAEM-RRQSV--DKGRAKHEEVKELYQRLPAGAE----- 512

  Fly  2485 EKPTEMTTVSTE------EEKQPTANCDNH 2508
              |.|.  ||.|      :|..||...||:
  Rat   513 --PYEF--VSLEWLQKWLDESTPTKPIDNN 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	107/396 (27%)
		UCH	2014..2377	CDD:278850	106/390 (27%)
		DUF3517	2723..>2877	CDD:288853
Usp48	XP_006239296.1	UCH	117..446	CDD:278850	106/389 (27%)
		Peptidase_C19L	118..447	CDD:239133	105/389 (27%)
		DUSP	512..582	CDD:283896	11/36 (31%)
		USP48_C	958..1064	CDD:176390

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810