Protein Alignment puf and Usp7

DIOPT Version :10

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: XP_063125353.1
• Gene: Usp7 / 360471
• RGDID: 1306915
• Length: 1161
• Species: Rattus norvegicus
• Alignment Length: 1115
• Identity: 226/1115 - (20%)
• Similarity: 381/1115 - (34%)
• Gaps: 321/1115 - (28%)

  Fly  2000 WDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLRVPPNAARKHGPTLLELQRM 2064
            ||      .:...|||||.|.||||||.|.:|.|:...|.|.||..:|...........|.|||:
  Rat   244 WD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRV 302

  Fly  2065 FAYLLESERKSYNPRSFCRVYQMDHQPLNTGEQKDMAEFFIDLVSKLEDMTPD--LKHLVKRLFC 2127
            | |.|:...|....:...:.:  ..:.|::..|.|:.|....|:..:|:....  ::..:.:||.
  Rat   303 F-YELQHSDKPVGTKKLTKSF--GWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFR 364

  Fly  2128 GSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRNLQESLDEVTVKDTLEGDNMYTCSQCGKKVRA 2192
            |.:.:.:...:..:.|...||:|.::..:...:|:.||..:....:.|:|||.|...:.|.: .|
  Rat   365 GKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EA 428

  Fly  2193 EKRACFKKLPQILCFNTMRYTFNMVTMLKEKVNTHFSFPLRLNMCHYVEKTLMPQQYKEERERRQ 2257
            ||...|..||.:|....||:.::..|....|:|..|.||.:|.:..:::||
  Rat   429 EKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKT-------------- 479

  Fly  2258 KEKEGADGSGDGNDNEKAEATLDDDIEECYEYELVGVTVHTGTADGGHYYSFIKERTKTSYHTHE 2322
                                    |.::...|.|..|.||:|...||||..::..:      ...
  Rat   480 ------------------------DPKDPANYILHAVLVHSGDNHGGHYVVYLNPK------GDG 514

  Fly  2323 RWFLFNDAEVKPFDPSQIAAECFGGEMTSKTYDSVTEKYLDFSFEKTNSAYMLFYERRLPEHLQR 2387
            :|..|:|         .:.:.|...|.....|....:   |.|.....:||||.|.|      :.
  Rat   515 KWCKFDD---------DVVSRCTKEEAIEHNYGGHDD---DLSVRHCTNAYMLVYIR------ES 561

  Fly  2388 RHSELLVTPT----PSPTVEEKSEAEEPTKMETSSSEIKADVDVEVEVEEKDKEKPAQTDTESKE 2448
            :.||:|...|    |...||   ..:|..::|....:.:.:..:.::|                :
  Rat   562 KLSEVLQAVTDHDIPQQLVE---RLQEEKRIEAQKRKERQEAHLYMQV----------------Q 607

  Fly  2449 TPAKEEIADDKSKQDEPEEK------KIEKQSREGE---EKSETDEKPTEMTTV-----STEEEK 2499
            ..|:::....:......|||      |:.|.|...|   ..|:|...|.:...:     .:...|
  Rat   608 IVAEDQFCGHQGNDMYDEEKVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTK 672

  Fly  2500 QPTANCDNHQQNNNSNSKASNDQQPST--------SKAAQKLQLFRPLLNKELEDWIWQDNRQFL 2556
            :| |..||....:.:..:.|:::.|.|        ..||....|  |..:|:
  Rat   673 RP-AMLDNEADGSKTMIELSDNENPWTIFLETVDPELAASGATL--PKFDKD------------- 721

  Fly  2557 QDRNIFEHTY------FNFMWQICGHIPQSLISETDVTCMAAKL------SVSFFIET--FIHAK 2607
            .|..:|...|      .|:    ||||      .|.::|....|      ...|..:|  .::.:
  Rat   722 HDVMLFLKMYDPKTRSLNY----CGHI------YTPISCKIRDLLPVMCDRAGFIQDTSLILYEE 776

  Fly  2608 EKPTMVPWV------------ELLTKQFNASQE------------ACEWFLSHMSQEPYWPVQVL 2648
            .||.:...:            ||:.......|:            |.|:|     ::.|..|.|:
  Rat   777 VKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYF-----RDLYHRVDVI 836

  Fly  2649 IQC----PN---------------QMVRQMFQRLVIHVIQQLRASHAHLYLEVETDEDDKELIGQ 2694
            . |    ||               |:.:.:.|||          :...:.|:....:..::..|.
  Rat   837 F-CDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRL----------NTDPMLLQFFKSQGYRDGPGN 890

  Fly  2695 ASCVTRFIGSLISLLEHGARANLRHLSEYFGLLCEFSRMGDEEAMYLLRIGVLKSLVDFYLGHKQ 2759
            .             |.|.....||.|.::|       :....:.:|..:   ||..:..:...:.
  Rat   891 P-------------LRHNYEGTLRDLLQFF-------KPRQPKKLYYQQ---LKMKITDFENRRS 932

  Fly  2760 TDSIDISSDNEDNSSEEALSVEKMRPASLDKMIALCASLVERSRGADFRLRLSPKDFSAIAGGKG 2824
            ...|.::|    ...||.:::...:...:..::..|...||....|..||||
  Rat   933 FKCIWLNS----QFREEEITLYPDKHGCVRDLLEECKKAVELGDKASGRLRL------------- 980

  Fly  2825 FPFLYQQIKDGINPHQTKHLIHALC-------RWDERLATQIIGMLFASVTKHTEL---CAPFFK 2879
            ...:..:|   |..||...|:..|.       |.:|....|:      .:.|..|:   .|.|.|
  Rat   981 LEIVSYKI---IGVHQEDELLECLSPATSRTFRIEEIPLDQV------DIDKENEMLITVAHFHK 1036

  Fly  2880 LLTLLTETQGGPVGLPCFTQL--------ILPRMWDAAEYCPQSVLDWLSLQATKNKIA------ 2930
            .:.       |..|:|...::        ::.|:        ||:||....:..|.|.|
  Rat  1037 EVF-------GTFGIPFLLRIHQGEHFREVMKRI--------QSLLDIQEKEFEKFKFAIVMMGR 1086

  Fly  2931 HAWILQSA-EKWLEQFLLAHDNTRVRNAAAFLLVALVPSQPFRANFRAHSQHKLLALNPHSYRDI 2994
            |.:|.:.. |..|:.| ......|:...|....|.|...||             |..:.|..|.|
  Rat  1087 HQYINEDEYEVNLKDF-EPQPGKRLSGVAVLWSVGLETVQP-------------LGGSSHGIRSI 1137

  Fly  2995 NSDAQAVLHQ 3004
            ::.|...|.|
  Rat  1138 SNGALLGLRQ 1147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	93/370 (25%)
		DUF3517	2648..>2884	CDD:463438	44/264 (17%)
		MDN1	<3661..>3887	CDD:444083
Usp7	XP_063125353.1	None