Protein Alignment puf and Usp40

DIOPT Version :9

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_001128357.1
• Gene: Usp40 / 316599
• RGDID: 1309613
• Length: 1235
• Species: Rattus norvegicus
• Alignment Length: 912
• Identity: 197/912 - (21%)
• Similarity: 342/912 - (37%)
• Gaps: 255/912 - (27%)

  Fly  1988 AQHKSGPK-------QPYPWDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLR 2045
            :|:.||.|       .|.|.::....         |:.|.|.|||::|.:|.|:..|:.|.|:..
  Rat    16 SQYGSGKKLKTKGLEPPAPREFTKLS---------GIRNQGGTCYLSSLLQTLHFTPEFREALFS 71

  Fly  2046 VPP----NAARKHGPTL------LELQRMFAYLL--ESERKSYNPRSFCRVYQMDHQPLNTGEQK 2098
            :.|    :...|..|..      |:|||:||.||  :.|..|....:....:..|.:.    .|.
  Rat    72 LGPEELGSLEDKDKPEAKVRIIPLQLQRLFAQLLLVDQEAASTTDLTDSFGWTSDEEM----RQH 132

  Fly  2099 DMAEFFIDLVSKLE-DMTPDLKH-LVKRLFCGSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRN 2161
            |:.|....|.|.|| .:.....| |:.||:.|::.|.:|..:|.:||...|||..:...|.::..
  Rat   133 DVQELNRILFSALETSLVGTSGHDLIHRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSG 197

  Fly  2162 LQESLDEVTVKDTL-EGDNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMRYTFNMVTMLKEKVN 2225
            |:::|..:.|::.: :.||:|.|..|.:.|:|.|.|..:|||..|..:.:|:.|:.|...:.|..
  Rat   198 LEDALWNMYVEEEIFDYDNLYHCGTCDRLVKAAKSAKLRKLPPFLTISLLRFNFDFVKCERYKDT 262

  Fly  2226 THFSFPLRLNMCHYVEKTLMPQQYKEERERRQKEKEGADGSGDGNDNEKAEATLDDDIEECYEYE 2290
            :.::||||:|:..:.|::.|                                   ||:|  |.|:
  Rat   263 SCYTFPLRINLKPFCEQSDM-----------------------------------DDME--YMYD 290

  Fly  2291 LVGVTVHTGTADGGHYYSFIKERTKT-SYHTHERWFLFNDA---------EVKPFDP-------- 2337
            |..|.:|.|...||||:.:||:.... ::...|.   .:|:         |.:..||
  Rat   291 LFSVIIHKGGCYGGHYHVYIKDVDHLGNWQCQEE---ISDSAVNLKAPQNEEETDDPLVVLKAIL 352

  Fly  2338 -----SQIAAECFGGEMTSKTYDSVTEKYLDFSFEKTNSAYMLFYERRLPEHLQRRHSELLVTPT 2397
                 :||..:..|.::..||..|..:||     .|.:.....|.         |.|.::.:..|
  Rat   353 LQEEANQIPVDQLGQKLLIKTGISWNKKY-----RKQHGPLRKFL---------RLHPQVFLLST 403

  Fly  2398 PSPTVE-EKSEAEEPTKMETSSSEIKADVDVEVEVEEKDKEKPAQTDTESKETPAKEEIADDKSK 2461
            ...||. ::|...:......|..:|         ......|.|...|..|  .|...:|.|.|.
  Rat   404 DESTVSLQRSHFPQVPSDPQSHEQI---------AHTLASEPPGLRDNIS--CPHWFDINDSKV- 456

  Fly  2462 QDEPEEKKIEKQSREGEE-------KSETDEKPTEMTTVSTEEEKQPTANCDNHQQNNNSN---- 2515
              :|.::|...|..:|:|       :..|.::|:|     .:...:....|...::.:.:|
  Rat   457 --QPIKEKDIMQQFQGKESAYMLFYRKATLQRPSE-----AQANPRYRVPCHLLKEMDAANVLLQ 514

  Fly  2516 -SKASNDQQPSTSKAAQKL----QLFRPLLNKELE--DWIWQ---DNRQFLQD--RNIFEHTYFN 2568
             .:|..|...||.:....|    :.|...|:..:.  :.:|.   |.|:.:.|  ::||:...|
  Rat   515 TRRAECDSANSTFELHLHLGPHYRFFNGALHPAVSQTESVWDLTFDKRKTVGDLRQSIFQLLEF- 578

  Fly  2569 FMWQ------ICGHIPQSL-----ISETDVTCMAAKLSVSFFIETFIHAKEKPTMVPW--VELLT 2620
              |:      :...:|..|     :...::|...|::           |.|:...| |  ||:..
  Rat   579 --WEGDMVLSVAKRVPAGLHVYHTLDGDELTLGEAEI-----------ADEEDIFV-WNGVEVGG 629

  Fly  2621 KQFNASQEACEWFLSH---------------MSQEPY----------------WPVQVLI----- 2649
            .|.....: ||..|.|               :.:.|:                .|..||:
  Rat   630 VQIQTGFD-CEPLLLHILHLELSGEGSECEQLVESPHVFPANAEVGTVFTALGTPEGVLLMNSVE 693

  Fly  2650 ----QC----PNQMVRQMFQRLVIHVIQQLRASHAHLYLEVETDEDDKELIGQASCVTRFIGSLI 2706
                :|    |.:.:::.|:.      |.||  :..|.|..::|.||..|:.:..   |:..|:.
  Rat   694 STDEECWTAIPQEDMKKTFRE------QGLR--NGSLILVQDSDSDDNSLLSKQG---RWTSSMN 747

  Fly  2707 SLLEHGARANLRHLSEYFGLLCEFSRMGDEEAMYLLRIGVLKSLVDFYLGHKQTDSIDISSDNED 2771
            .|       |...:.       .|.:.|.||..  ::|.|....|.|.:..|....:.:..:..:
  Rat   748 EL-------NWLQVK-------NFCQSGSEEKQ--VQIAVTMHTVVFDIRIKAIKELKLMKELAE 796

  Fly  2772 NS 2773
            ||
  Rat   797 NS 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	104/406 (26%)
		UCH	2014..2377	CDD:278850	103/400 (26%)
		DUF3517	2723..>2877	CDD:288853	11/51 (22%)
Usp40	NP_001128357.1	peptidase_C19C	40..381	CDD:239124	100/393 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900