Protein Alignment puf and Usp30

DIOPT Version :10

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 147/701 - (20%)
• Similarity: 220/701 - (31%)
• Gaps: 241/701 - (34%)

  Fly  1765 LLWAPTGTDHCRWLQKFILEDPEPAVRREICAGLYRI---CLGNAHSYRLLLAPLLHKLIALLPL 1826
            :.|.|:|:   |..|           ||...|||:..   |..|.....:...|   :.||.|.|
  Fly    22 VFWGPSGS---RLRQ-----------RRGQIAGLHNFGLTCFLNTLLQAMAACP---QFIAWLQL 69

  Fly  1827 AEQMSSGNQH--TQFLLSEE---------GKDPYGPACRDYFWLLARLVDTLSPEMVAEEHIDIE 1880
            ....|...:.  |..|.:.|         ..|||.|..      :.|.::.|...:..|||
  Fly    70 YNNASPDRKSLITSMLNTLEVVNGTHATLRGDPYSPGA------VLRALNALGWVIPQEEH---- 124

  Fly  1881 MLCESISQSILTREYYELRHGYQDDGLVGLLNLMSNLIKYDTTFKYTPKALSFIEQLIGFLFD-M 1944
                         :.:||.|       |.|..|....|:               .|.:|.|.| :
  Fly   125 -------------DAHELFH-------VLLTCLEEEAIR---------------PQPLGCLSDAL 154

  Fly  1945 PSPADRQKPKCKSASSRASAYDLLVELCRGCAT------NYAYLHGRLLAQHKSG--PKQP---- 1997
            |:..|       ..||.|           |.||      :::.:...|.|..:.|  |.:|
  Fly   155 PTDND-------DNSSLA-----------GTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAM 201

  Fly  1998 ----YPWDYWPRDEG-------RAE----------CGYVGLTNLGATCYMASCVQHLYMMPQARA 2041
                ...:|   ||.       |:|          |...|...||:....|......:..|
  Fly   202 LTDFLNMEY---DESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFP---- 259

  Fly  2042 AVLRVPPNAA-------RKHGPTLLELQRMFAYLLESERKSYNPRSFCRVYQMDHQPLNTGEQKD 2099
             ::..|.:.|       |...|.|.:.|:.     :.|..:....|.||..:..|:    |..:
  Fly   260 -LVSNPDSLATPMLGGERSSRPRLPQSQQQ-----QDEGLNRRVSSSCRSLERLHR----GPGR- 313

  Fly  2100 MAEFFIDLVSKLEDMTPDLKHLVKRLFCGSLSNNVVSLDCGHVSRTAED-FYTVRCQVADMRNLQ 2163
                    ||...:|.|.   .|...|.|::...:|...||..|....| |.::...:...|...
  Fly   314 --------VSIWSNMMPS---QVAHPFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLPPQRRTG 367

  Fly  2164 ESL-----DEVTVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMRYTFNMVT--MLK 2221
            .||     :.:|.:|..:    ..|..|.:.....|...|.|||..||.:..| |..:.|  :.|
  Fly   368 LSLGHLLSEYITSEDLSD----VKCDSCNETTTHTKSVTFAKLPACLCIHVAR-TVWLPTGQVCK 427

  Fly  2222 EKVNTHFSFPLRLNMCHY--VEKTLMPQQ----------YKEERERRQKEKEGADGSGDGNDNEK 2274
            .|...|  ||..|:|..|  |:..|..|.          |.......       :|.|.|   |.
  Fly   428 RKDYVH--FPESLSMAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMN-------NGVGGG---EG 480

  Fly  2275 AEATLDDDIEECYEYELVGVTVHTGTADGGHYYSFIKERTKTSYHTHERWFLFNDAEVKPFDPSQ 2339
            .......::     |.|:.|.||:|.|:.||:.::    .:.|.....||:..:|..|:
  Fly   481 FGTMFPKNL-----YRLLAVVVHSGEANSGHFVTY----RRGSLRNAHRWYYTSDTIVR------ 530

  Fly  2340 IAAECFGGEMTSKTYDSVTEKYLDFSFEKTNS--AYMLFYERRLPEHLQRR 2388
                                   :.|.::..|  ||:|||:|.....|..|
  Fly   531 -----------------------EVSIDEVLSVPAYLLFYDRGQQRQLNLR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	85/397 (21%)
		DUF3517	2648..>2884	CDD:463438
		MDN1	<3661..>3887	CDD:444083
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	29/132 (22%)
		Peptidase_C19F	<323..548	CDD:239127	62/282 (22%)