Protein Alignment puf and Usp26

DIOPT Version :10

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_001100418.1
• Gene: Usp26 / 302488
• RGDID: 1563443
• Length: 827
• Species: Rattus norvegicus
• Alignment Length: 726
• Identity: 136/726 - (18%)
• Similarity: 244/726 - (33%)
• Gaps: 242/726 - (33%)

  Fly  1874 EEHIDIEMLC-ESISQS--ILTREYYELRHGYQDDGLVGLL-------------------NLMSN 1916
            |.|:.....| ||..:|  .|.|:...|.........||||                   ||..:
  Rat   132 EGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFMKRKRFFLGAEKEKQNLKGS 196

  Fly  1917 LIKYDTTF-------KYTPKALSFIE-QLIGFLFDMPSPADRQKPKCKSASSRASAYDLLVELCR 1973
            ..:::|..       |...:.:..:| ...||.|    |.:...|:..|.:.| ...||:.:|..
  Rat   197 TREFETNLVVSISNEKGKERGVRAVEISKAGFGF----PFETNYPEEGSVNVR-DLNDLITKLFS 256

  Fly  1974 GC--ATNY--------AYLHGRLLAQHKSGPKQPYPWDYWPRDEGRAECGYVGLTNLGATCYMAS 2028
            ..  .|:|        .|:...||...||       |.              ||.|:|.|||:..
  Rat   257 PLLFETHYIENGLDWHEYMETFLLDPEKS-------WQ--------------GLPNVGNTCYINV 300

  Fly  2029 CVQHLYMMP-------QARAAVLRVPPNAARKHGPTLLELQRMFAYLLESERKSYNPRS------ 2080
            .:|.|..:|       ......::.|.:........||.|:.:           ||.|:
  Rat   301 VLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDI-----------YNARTRQKLLI 354

  Fly  2081 --------FCRVYQMDHQPLNTGEQKDMAEFF-------------IDLVSKLEDMTPDLKHLVKR 2124
                    |..|:..|       .|.|..||.             ::::.:.|:.:.|. :|::.
  Rat   355 GITKALPIFGEVFAAD-------RQNDAHEFLSLCLVQLKETVQRVNMMWQSENESGDY-YLLRE 411

  Fly  2125 LFCGSLSNNVVSLDCGHVSRTAEDF-----YTVRCQVADM-----------------------RN 2161
            :|.     |..|::...|.....:|     .::.|:...:                       .:
  Rat   412 IFA-----NYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQNMS 471

  Fly  2162 LQESLDEVTVKDTLEGDNMYTCSQC--GKKVRAEKRACFKKLPQILCFNTMRYTFNMVTML-KEK 2223
            :|.|||.....:.||    :.|.:|  .|.|...|   |.:||:::..:..||:|:...:: |::
  Rat   472 IQSSLDLFFRAEELE----HRCERCLYNKSVALHK---FGRLPRVIIVHLKRYSFSESRIMNKDE 529

  Fly  2224 VNTHFSFPLRLNMCHYVEKT-----LMPQQYKEERE-RRQKEKEGAD----GSGDG-NDNEKAEA 2277
            .:...|..|||: ||..:.|     |:|.::.:..: .|..|:.|::    .|..| ....|...
  Rat   530 QHIVISKYLRLS-CHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRSKVFP 593

  Fly  2278 TLDDDIEECYEYELVG----VTVHTGTA---DGGHYYSFIKERTKTSYHT--HERWFLFNDAEVK 2333
            |:  :|....|.|:..    ..|.:|:|   |.|...:.::........|  ||:.::.:|
  Rat   594 TV--NIRSDKELEVQNGKRVSEVSSGSAQQEDPGKGANVVRSELTNETETIKHEKEYVLSD---- 652

  Fly  2334 PFDPSQIAAECFGGEMTSKTYDSVTEKYLDFSFEKTNSAYMLFYERRLPEHLQRRHSELLVTPTP 2398
             .|...|:.     |.:.|..::          ||.|                   .|.|....|
  Rat   653 -LDSGSISE-----ERSQKCQEA----------EKCN-------------------KEALPQSCP 682

  Fly  2399 SPTVEEKSE-AEEPTKMETSSSEIKADVDVEVEVEEKDKEKPAQTDTESKETPAKEEIADDKSKQ 2462
            .|:.:|::| ..:|....|.:..:.                 :|..::|.::|...::.|.....
  Rat   683 KPSSQEQTENLGKPAVSHTQNGSLS-----------------SQGSSDSSKSPGCNDVFDKAKPT 730

  Fly  2463 DEPEEKKIEKQ 2473
            .:.|.:|:.::
  Rat   731 SKVEPQKLNQK 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	86/453 (19%)
		DUF3517	2648..>2884	CDD:463438
		MDN1	<3661..>3887	CDD:444083
Usp26	NP_001100418.1	UCH_N	3..103	CDD:465227
		Peptidase_C19	181..>378	CDD:470612	45/240 (19%)
		UCH	288..557	CDD:425685	59/300 (20%)
		Peptidase_C19	<740..805	CDD:470612	0/2 (0%)