Protein Alignment puf and Usp7

DIOPT Version :9

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: XP_006522201.1
• Gene: Usp7 / 252870
• MGIID: 2182061
• Length: 1143
• Species: Mus musculus
• Alignment Length: 1044
• Identity: 212/1044 - (20%)
• Similarity: 359/1044 - (34%)
• Gaps: 306/1044 - (29%)

  Fly  2000 WDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLRVPPNAARKHGPTLLELQRM 2064
            ||      .:...|||||.|.||||||.|.:|.|:...|.|.||..:|...........|.|||:
Mouse   246 WD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRV 304

  Fly  2065 FAYLLESERKSYNPRSFCRVYQMDHQPLNTGEQKDMAEFFIDLVSKLEDMTPD--LKHLVKRLFC 2127
            | |.|:...|....:...:.:  ..:.|::..|.|:.|....|:..:|:....  ::..:.:||.
Mouse   305 F-YELQHSDKPVGTKKLTKSF--GWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFR 366

  Fly  2128 GSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRNLQESLDEVTVKDTLEGDNMYTCSQCGKKVRA 2192
            |.:.:.:...|..:.|...||:|.::..:...:|:.||..:....:.|:|||.|...:.|.: .|
Mouse   367 GKMVSYIQCKDVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EA 430

  Fly  2193 EKRACFKKLPQILCFNTMRYTFNMVTMLKEKVNTHFSFPLRLNMCHYVEKTLMPQQYKEERERRQ 2257
            ||...|..||.:|....||:.::..|....|:|..|.||.:|.:..:::||
Mouse   431 EKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKT-------------- 481

  Fly  2258 KEKEGADGSGDGNDNEKAEATLDDDIEECYEYELVGVTVHTGTADGGHYYSFIKERTKTSYHTHE 2322
                                    |.::...|.|..|.||:|...||||..::..:      ...
Mouse   482 ------------------------DPKDPANYILHAVLVHSGDNHGGHYVVYLNPK------GDG 516

  Fly  2323 RWFLFNDAEVKPFDPSQIAAECFGGEMTSKTYDSVTEKYLDFSFEKTNSAYMLFYERRLPEHLQR 2387
            :|..|:|         .:.:.|...|.....|....:   |.|.....:||||.|.|      :.
Mouse   517 KWCKFDD---------DVVSRCTKEEAIEHNYGGHDD---DLSVRHCTNAYMLVYIR------ES 563

  Fly  2388 RHSELLVTPT----PSPTVEEKSEAEEPTKMETSSSEIKADVDVEVEVEEKDKEKPAQTDTESKE 2448
            :.||:|...|    |...||   ..:|..::|....:.:.:..:.::|                :
Mouse   564 KLSEVLQAVTDHDIPQQLVE---RLQEEKRIEAQKRKERQEAHLYMQV----------------Q 609

  Fly  2449 TPAKEEIADDKSKQDEPEEK------KIEKQSREGE---EKSETDEKPTEMTTV-----STEEEK 2499
            ..|:::....:......|||      |:.|.|...|   ..|:|...|.:...:     .:...|
Mouse   610 IVAEDQFCGHQGNDMYDEEKVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTK 674

  Fly  2500 QPTANCDNHQQNNNSNSKASNDQQPST--------SKAAQKLQLFRPLLNKELEDWIWQDNRQFL 2556
            :| |..||....|.:..:.|:::.|.|        ..||....|  |..:|:
Mouse   675 RP-AMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATL--PKFDKD------------- 723

  Fly  2557 QDRNIFEHTY------FNFMWQICGHIPQSLISETDVTCMAAKL------SVSFFIET--FIHAK 2607
            .|..:|...|      .|:    ||||      .|.::|....|      ...|..:|  .::.:
Mouse   724 HDVMLFLKMYDPKTRSLNY----CGHI------YTPISCKIRDLLPVMCDRAGFIQDTSLILYEE 778

  Fly  2608 EKPTMVPWV------------ELLTKQFNASQE------------ACEWFLSHMSQEPYWPVQVL 2648
            .||.:...:            ||:.......|:            |.|:|     ::.|..|.|:
Mouse   779 VKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYF-----RDLYHRVDVI 838

  Fly  2649 IQC----PN---------------QMVRQMFQRLVIHVIQQLRASHAHLYLEVETDEDDKELIGQ 2694
            . |    ||               |:.:.:.|||          :...:.|:....:..::..|.
Mouse   839 F-CDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRL----------NTDPMLLQFFKSQGYRDGPGN 892

  Fly  2695 ASCVTRFIGSLISLLEHGARANLRHLSEYFGLLCEFSRMGDEEAMYLLRIGVLKSLVDFYLGHKQ 2759
            .             |.|.....||.|.::|       :....:.:|..:   ||..:..:...:.
Mouse   893 P-------------LRHNYEGTLRDLLQFF-------KPRQPKKLYYQQ---LKMKITDFENRRS 934

  Fly  2760 TDSIDISSDNEDNSSEEALSVEKMRPASLDKMIALCASLVERSRGADFRLRLSPKDFSAIAGGKG 2824
            ...|.::|    ...||.:::...:...:..::..|...||....|..||||
Mouse   935 FKCIWLNS----QFREEEITLYPDKHGCVRDLLEECKKAVELGDKASGRLRL------------- 982

  Fly  2825 FPFLYQQIKDGINPHQTKHLIHALC-------RWDERLATQIIGMLFASVTKHTEL---CAPFFK 2879
            ...:..:|   |..||...|:..|.       |.:|....|:      .:.|..|:   .|.|.|
Mouse   983 LEIVSYKI---IGVHQEDELLECLSPATSRTFRIEEIPLDQV------DIDKENEMLITVAHFHK 1038

  Fly  2880 LLTLLTETQGGPVGLPCFTQL--------ILPRMWDAAEYCPQSVLDWLSLQATKNKIA------ 2930
            .:.       |..|:|...::        ::.|:        ||:||....:..|.|.|
Mouse  1039 EVF-------GTFGIPFLLRIHQGEHFREVMKRI--------QSLLDIQEKEFEKFKFAIVMMGR 1088

  Fly  2931 HAWI 2934
            |.:|
Mouse  1089 HQYI 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	94/370 (25%)
		UCH	2014..2377	CDD:278850	91/364 (25%)
		DUF3517	2723..>2877	CDD:288853	28/163 (17%)
Usp7	XP_006522201.1	COG5077	96..1141	CDD:227409	212/1044 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810