Protein Alignment puf and C34F6.9

DIOPT Version :10

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_001366881.1
• Gene: C34F6.9 / 181312
• WormBaseID: WBGene00007943
• Length: 1181
• Species: Caenorhabditis elegans
• Alignment Length: 1161
• Identity: 213/1161 - (18%)
• Similarity: 338/1161 - (29%)
• Gaps: 442/1161 - (38%)

  Fly  1453 LATKRKQIKQKFRDLLDPNNLQKFMYSLHIVESLALTSSRRGESNGN-VAMGNTPEQVRVKKSSM 1516
            ||.:.|.:|.....  |..|.:|.:.|....:|..|  ..:|..|.| ||   :|::...:|||:
 Worm   131 LANQLKSLKGIITK--DSFNSEKSLASFSYADSFFL--KMKGVHNNNEVA---SPDEKVQEKSSV 188

  Fly  1517 --------------------GRRRNSN------EQPPPPPPEVKMSK---------EQLCELEAP 1546
                                |..:|..      ..||..|..|..||         .:|.|....
 Worm   189 SPVIPNEAVVSKMNEYLDETGSAKNLEAHVKPVSDPPASPGRVISSKMLSSRSNDENKLLENAVE 253

  Fly  1547 LTPT--PSTG-------LQDVETEASSSSGGDKENQPKQ----------HSKRQKKGETFEQEKE 1592
            ..||  |.|.       |.|::.|.::|. .|...||..          |....:..:..:..|:
 Worm   254 TLPTVLPQTDYAENEKFLNDIQVETNNSI-SDHTRQPSNEPVEKVSESAHDLTSQISQCTDLLKD 317

  Fly  1593 RP----------VGCSTPPSPTPPPPALSVVERGDNKW-----------------SEAFVKCGGL 1630
            .|          .|.::..:...||..::     |.|:                 ||...|....
 Worm   318 HPESSETTSNTSAGVASATTDQTPPDVVA-----DQKYNVTTPIDPSHIVLTSPHSEFDKKEESS 377

  Fly  1631 RHLYEIFSEGQ-LQQSAHPKELALNEWRHDCLASLLRILWLLGFEELQSADAHVLMSRP--HPFM 1692
            ..::....|.. |..|..||:       :|.:     :|.|....|:......:|:..|  .|..
 Worm   378 EQIHNNNMENDALHNSTFPKQ-------NDVV-----MLELFKASEISEVPLSILVVVPISEPSS 430

  Fly  1693 LQLMEVPQCLTRLSSILNDEVHQQHQASSANP---------------------LVFPYQFQHLRT 1736
            :...:|.   |.|...|.|....|...||.||                     |:.......||.
 Worm   431 VSTTDVS---TTLDDALQDLPISQVVESSQNPVEEKTMSSETAVSLNLPCVNTLITEADEVKLRD 492

  Fly  1737 GFWGRAQLIQFAMNILVSFVHASAEARRLLWAPTGT-------DHCRWLQKFILEDPEPAV---- 1790
            ..|.:.:..|..::           .:.::|:.|.|       ...:...|...:.|:|||
 Worm   493 ALWEKRKREQEKLH-----------NKTIIWSRTVTYPPIHTFPKTKKYVKQAAKIPQPAVLKED 546

  Fly  1791 ---------RREICAGLYRI-----------CLGNAHSYRLLLAPLLHKLIALLPLAEQMSSGNQ 1835
                     ::::.|| |.:           .|..:||...|:.....:|.|:..:   :::|.|
 Worm   547 PQAVKPRPPKKDVLAG-YSVETIFLALTGETVLCRSHSLEDLVRLKQEELDAVTSI---LNNGVQ 607

  Fly  1836 HTQ--------FLLSEEGKDPYG-----PACRDYFWLLARLVDTLSPEMVA-------------- 1873
            .:|        .|.|::.|:..|     |...::     .:..|::..|:.
 Worm   608 KSQCDSGVMSNTLKSQDRKESEGVQLNSPLPENH-----AVNQTVNQSMIRKGRPKRSTKTKSGS 667

  Fly  1874 -----------------EEHIDIEMLCESI------------SQSILT-------------REYY 1896
                             :|..|||...::|            |:|.:|             :|.:
 Worm   668 ETENESMSEDNDDFSEHDEDFDIEQAVQAIDNVHHKAKRERKSRSSITVSEDGYPPETVSPQELH 732

  Fly  1897 EL-RHGYQDDGLVGLLNLMSNLIKYDTT----FKYTPKALSFIEQLIGFLFDMPSPADRQK---- 1952
            .| |....||.........|:.:|..|.    |.|.|......||      |......|:|
 Worm   733 SLKRKSLPDDNTTPSKQRRSSRLKNSTAKTADFVYEPAVTDRSEQ------DKSPSLPREKNIGK 791

  Fly  1953 --PKCKSASSRASA------------------YDLLVELCRGCATNYAYLHGRLLAQHKSGPKQP 1997
              .|.:.||.|:|:                  :...||......:|...   :.|.|....||..
 Worm   792 DSGKSRLASQRSSSRRSSAPFSEESPSTKKTRFSTRVEQYSRRVSNETI---KSLLQQVLTPKAA 853

  Fly  1998 YP---WDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLRVPPNAARKHGPTLL 2059
            ..   .|::|....|.     .:.|....||..|.||.|..:||..:.|        |.|.....
 Worm   854 DECDIQDHFPSPIVRR-----AIVNRNTLCYAISMVQLLMRVPQVYSIV--------RSHSHKKQ 905

  Fly  2060 ELQR----------------------MFAYLLES--------------ERKSYNPRSFCRVYQMD 2088
            :..|                      .|..||:|              |...|....|...|...
 Worm   906 KANRSECFLCMLTNLISERPRADDTPAFVALLKSNWKNIEDEGMQCVMEAMQYFFNKFDEEYMHA 970

  Fly  2089 HQPLNTGEQKDMAEFFIDLVSKLEDMTPDLKHLVKRLFCGSLSNNVVSLDCGHVSRTAEDFYTVR 2153
            |.|:.       :.|.|::....|              |.|         |.|||...:....|.
 Worm   971 HPPIR-------SYFEIEMFIAYE--------------CKS---------CKHVSNAPDKAIYVS 1005

  Fly  2154 CQVADMR--NLQESLDEVTVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMRYTFNM 2216
            ..::...  .:|..:|::.....:.|.|   |..||::....... |.|||::|.:
 Worm  1006 IDLSSKTKGTMQSMVDKMANPIPVVGMN---CKSCGQETLCSTTR-FTKLPEVLLY--------- 1057

  Fly  2217 VTMLKEKVNTHFSFPLRLNMCHYVEKTLMPQQYKEERERRQKEKEGADGSGDGND----NEKAEA 2277
                                       .:|:...::|               |.|    |.:.:.
 Worm  1058 ---------------------------FVPRVKDQQR---------------GKDMTVLNVQRQL 1080

  Fly  2278 TLDDDIEECYEYELVGVTVHTG-TADGGHYYSFIKERTKTSYHTHERWFLFNDAEV 2332
            .|.|| ...:.|||.....|.| ..|.|||.||..:||....:..     ::||:|
 Worm  1081 ILKDD-NNAHNYELCSFIAHCGKNGDNGHYKSFEVDRTNEFQYNE-----YDDAKV 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	69/363 (19%)
		DUF3517	2648..>2884	CDD:463438
		MDN1	<3661..>3887	CDD:444083
C34F6.9	NP_001366881.1	Peptidase_C19	949..1130	CDD:239072	51/271 (19%)