Protein Alignment puf and usp-14

DIOPT Version :9

• Sequence 1: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Sequence 2: NP_497006.1
• Gene: usp-14 / 175105
• WormBaseID: WBGene00006856
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 130/624 - (20%)
• Similarity: 206/624 - (33%)
• Gaps: 205/624 - (32%)

  Fly  1864 VDTLSPEMVAEEHIDIEMLCESISQSILTREYYELR-HGYQDDGLVGLLNLMSNLIKYDTTFKYT 1927
            |||.:|.||.:..:      .:::|.:..|:...:. ....||...|:      .||.:.|.
 Worm    17 VDTSAPPMVFKAQL------FALTQVVPERQKVVIMGRTLGDDDWEGI------TIKENMTI--- 66

  Fly  1928 PKALSFIEQLIGFLFDMPSPADRQKPKCKSASSRASAYDLLVELCRGCATNYAYLHGRLLAQHKS 1992
                    .::|.:.::|.|....:.|..:...:|.....|
 Worm    67 --------MMMGSVGEIPKPPTVLEKKQANRDKQAEEISAL------------------------ 99

  Fly  1993 GPKQPYPWDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARAAVLR-VPPNAARKHGP 2056
                 ||            |   ||.|||.|||..||||   |:.:....||: ......|:|..
 Worm   100 -----YP------------C---GLANLGNTCYFNSCVQ---MLKEVNELVLKPAEEMRIREHND 141

  Fly  2057 TLL-ELQRMFAYLLESER----KSYNPRSFCRVYQM-DHQP-LNTGEQKDMAEFFIDLVSKLEDM 2114
            .|. .|..:|..|.:.:|    |....:.|..:..: |..| ....:|:|..|..:.::|.
 Worm   142 RLCHNLATLFNSLRDKDRALRSKGEPIKPFAAILTLSDSFPQFEKFKQQDANECLVSIMSN---- 202

  Fly  2115 TPDLKHLVKRLFCGSLSNNVVSLDCGHVSRTAEDFYTVRCQVADMRNLQESLDEVTVKDTLEGDN 2179
                   |.|:: |....|:.||              .|.|........|| |||:.| .:|.:|
 Worm   203 -------VTRIY-GLSGWNIESL--------------FRIQTETTMKCLES-DEVSEK-KVERNN 243

  Fly  2180 MYTC-------------------------SQCGKKVRAEKRACFKKLPQILCFNTMRYTFNMVTM 2219
            ..||                         .:..:..:.:|.....:||:.|..|..|:.:...|.
 Worm   244 QLTCYVNQDVRFLQTGIKAGFEEEMTRNSEELNRDAKWQKNTQISRLPKYLTVNINRFFYKESTK 308

  Fly  2220 LKEKVNTHFSFPLRLNMCHYVEKTL------------MPQQYKEERERRQKEKEGADGSGDGNDN 2272
            ...|:.....||::|:......:.|            :.:..|.|||.|:|..:...|....:|.
 Worm   309 TNAKILKSVQFPMQLDTYDLCSQELKDKLVARRADIKLEEDAKLERELRKKVLDKEQGDKIFDDG 373

  Fly  2273 EKAEATLDDDI--EECYEYELVGVTVHTG-TADGGHYYSFIKERTKTSYHTHERWFLFNDAEVKP 2334
            .......:||.  .....|:|.|:..|.| ::..|||.::::.      ....:|.||:|..|..
 Worm   374 VALPTAFEDDAGSNNSGFYDLKGIITHKGRSSQDGHYVAWMRS------SEDGKWRLFDDEHVTV 432

  Fly  2335 FDPSQIAAECFGGEMTSKTYDSVTEKYLDFSFEKTNSAYMLFYERRL----PEHLQRRHSELLVT 2395
            .|...|.....||:.                    :|||:|.||.|:    ||          :.
 Worm   433 VDEEAILKTSGGGDW--------------------HSAYVLLYEARVIKQFPE----------LP 467

  Fly  2396 PTPSPTVEEKSEAEEPTKMETSSSEIKADVDVEVEVEEK 2434
            |.|.||                  |:.||....:||.||
 Worm   468 PAPVPT------------------EVAADTAEPMEVSEK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	94/420 (22%)
		UCH	2014..2377	CDD:278850	91/410 (22%)
		DUF3517	2723..>2877	CDD:288853
usp-14	NP_497006.1	UBQ	1..71	CDD:294102	14/76 (18%)
		UBQ	4..71	CDD:214563	14/76 (18%)
		UCH	101..455	CDD:278850	93/425 (22%)
		Peptidase_C19A	103..456	CDD:239122	91/409 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910