DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atl and atl1

DIOPT Version :9

Sequence 1:	NP_001287506.1	Gene:	atl / 42934	FlyBaseID:	FBgn0039213	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_012824050.2	Gene:	atl1 / 779669	XenbaseID:	XB-GENE-945669	Length:	558	Species:	Xenopus tropicalis

Alignment Length:	511	Identity:	290/511 - (56%)
Similarity:	385/511 - (75%)	Gaps:	15/511 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VQVINASEEHTFVLNEDALSEVLMRDEVKDRFVCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHD 70
            |||:...::|:|.|:|.||:.:|:.:.|:|:.|..||||||||||||||:||.|||||..    |
Frog    35 VQVLVVKDDHSFELDEAALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYKT----D 95

  Fly    71 ATDWLGGESDPLEGFSWRGGSERDTTGILMWSDIFLHDYPNGDKIAIILLDTQGAFDSQSTVRDC 135
            ..||||..::||.||||||||||:||||.:||:|||.:.|:|:|:|::|:||||.||||||:||.
Frog    96 TVDWLGDYNEPLSGFSWRGGSERETTGIQIWSEIFLVENPDGNKVAVLLMDTQGTFDSQSTLRDS 160

  Fly   136 ATVFALSTMLSSVQIYNLSQNIQEDDLQHLQLFTEYGRLALADTGKKPFQRLQFLVRDWSFPYEA 200
            |||||||||:||:|:||||||:||||||||||||||||||:.:|..||||.|.|||||||||||.
Frog   161 ATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEF 225

  Fly   201 EYGALGGDKILKRRLEVSDKQHPELQSLRRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDIT 265
            .||:.||:|.|::||:||:.||.|||::|:||.||||.::|||||||||.|||||.|||:|::|.
Frog   226 PYGSDGGNKFLEKRLKVSENQHEELQNVRKHIHSCFTNISCFLMPHPGLTVATNPNFDGKLKEID 290

  Fly   266 PEFKSSLRSLVPMLLAPDNLVYKEISGQRVRARDLIQYFQSYMNIYKGNELPEPKSMLVATAEAN 330
            .||..:|:..:|.||:|:||..|||||.|:..|.|::||::|:.||:|.|||.|||||.||||||
Frog   291 EEFIKNLKVFIPWLLSPENLDVKEISGNRITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEAN 355

  Fly   331 HLTAVAAAKELYGQLMEEVCGGTRPYLSTAHLQTEHLRVKDKALFQFAAKRKMGGEEFTEKFRKQ 395
            :|.|||.||:||.:.|||||||.||:|:...||..|..:|::|:..|...:|||||||:.::.:|
Frog   356 NLAAVATAKDLYNKNMEEVCGGDRPFLAPTDLQQRHQHLKEEAVKLFRGVKKMGGEEFSRRYLQQ 420

  Fly   396 LEDDLEEVFTNYQAHNESKNIFKAARTPAVYFACAVIMYILSGIFGLVGLYTFANFCNLVMGVAL 460
            ||::::|::..|..||:|||||.||||||..|....|.|:|:.:.|.:||...|:.||::||:.|
Frog   421 LENEIDELYVQYIKHNDSKNIFHAARTPATLFVVIFITYVLAAVTGFIGLDIIASLCNMIMGLTL 485

  Fly   461 LTLALWAYIRYSGELSDFGGKLDDFATLLWEKFMRPIYHGCMEKGIHHV----ATH 512
            :||..|||||||||..:.|..:|..|..||::       |...:.::.:    |||
Frog   486 ITLCTWAYIRYSGEYRELGAVIDQVAAALWDQ-------GSTNEALYKLYSAAATH 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atl	NP_001287506.1	GBP	14..289	CDD:280433	177/274 (65%)
atl	NP_001287506.1	MSC	<316..>471	CDD:286487	81/154 (53%)
atl1	XP_012824050.2	GBP	43..314	CDD:308078	177/274 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	383	1.000	Domainoid score	I820
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	613	1.000	Inparanoid score	I891
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	1	1.000	-	-		FOG0001595
OrthoInspector	1	1.000	-	-		otm49367
Panther	1	1.100	-	-	O	PTHR10751
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1147
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160