DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atl and Gbp3

DIOPT Version :9

Sequence 1:	NP_001287506.1	Gene:	atl / 42934	FlyBaseID:	FBgn0039213	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_038959795.1	Gene:	Gbp3 / 685116	RGDID:	1597766	Length:	1255	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	98/415 - (23%)
Similarity:	172/415 - (41%)	Gaps:	85/415 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDATDWLGGESDPLEGFSWRGGSERDTTGILMWS 102
            |.||::.|.:|.|||:|:                 :.|.|:::   ||........:|.||.||
  Rat   671 VVVVAIVGMYRTGKSYLM-----------------NCLAGQNN---GFPLGCTVXSETKGIWMW- 714

  Fly   103 DIFLHDYPNGDKIAIILLDTQGAFD-SQSTVRDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQ 166
               ...:|......:|||||:|..| .:...|:.|.:|||:.:|||..:||....|..|.|:.|.
  Rat   715 ---CVPHPTKPSHTLILLDTEGLGDVEKGDARNDAWIFALAVLLSSTFVYNSMSTINNDALEKLH 776

  Fly   167 LFTEYGRLALADTGKKP------------FQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEVSD 219
            ..|:...|..|.:..:.            |....:.|||::...:.:...:..|:.|:..|::..
  Rat   777 YVTKLTELIRAKSSPRSDGIEDAREFVGFFPDFIWTVRDFTLELKLDGHCITEDQYLENALQLVP 841

  Fly   220 KQHPELQSL---RRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDIT-----PEFKSSLRSLV 276
            .|.|:.|:.   |..|...|....||:...|    .::|:...:::.|:     |.|:..|.:..
  Rat   842 GQDPQTQTSNWPRECIRQFFPRRKCFVFDWP----VSDPQLLAKIESISESQLNPNFQKQLENFC 902

  Fly   277 PMLLAPDNLVYKEISGQRV---------RARDLIQYFQSYMNIYKGNELPEPKSMLVATAEANHL 332
                   :.::...:|:|:         |..:|:   |:|::......:|..::.:...||..:.
  Rat   903 -------SYIFSHATGKRLGEGILVTGSRLGNLV---QTYVDAINTGTVPCLENAVKTLAERENS 957

  Fly   333 TAVAAAKELYGQLMEEVCGGTRPYLSTAHLQ---TEHLRVKDKALFQFAAKRKMGGEEFTE---K 391
            |||..|.|.|.:.|.:     |..|.|..||   :.|...:.:|:..|..      ..|.:   |
  Rat   958 TAVQKAAEHYSEQMAQ-----RVRLPTDTLQELLSVHSACEKEAIAVFME------HSFKDDQWK 1011

  Fly   392 FRKQLEDDLEEVFTNYQAHNESKNI 416
            |:|:|...:||....:...|||.::
  Rat  1012 FQKKLVVTIEERKKVFMEQNESASL 1036

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atl	NP_001287506.1	GBP	14..289	CDD:280433	64/271 (24%)
atl	NP_001287506.1	MSC	<316..>471	CDD:286487	28/107 (26%)
Gbp3	XP_038959795.1	GBP	18..280	CDD:308078
		GBP_C	282..578	CDD:397124
		GBP	651..914	CDD:308078	65/277 (23%)
		GBP_C	916..1209	CDD:397124	32/135 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335784
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850