DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atl and Gbp10

DIOPT Version :9

Sequence 1:	NP_001287506.1	Gene:	atl / 42934	FlyBaseID:	FBgn0039213	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001034735.2	Gene:	Gbp10 / 626578	MGIID:	4359647	Length:	611	Species:	Mus musculus

Alignment Length:	471	Identity:	107/471 - (22%)
Similarity:	178/471 - (37%)	Gaps:	99/471 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EEHT--FVLNEDALSEVLMRDEVKDRF---VCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDAT 72
            |.|.  ..:|::|:       |:.|:.   |.||::.|..|.|||:|:
Mouse    13 ENHNEQLSVNQEAI-------EILDKISQPVVVVAIVGWSRTGKSYLM----------------- 53

  Fly    73 DWLGGESDPLEGFSWRGGSERDTTGILMWSDIFLHDYPNGDKIAIILLDTQGAFD-SQSTVRDCA 136
            :.|.|::   .||......:..|.||.||    ...:|...:..::||||:|..| .:...::..
Mouse    54 NCLAGQN---HGFPLGSTVQSQTKGIWMW----CMPHPTKPEHTLVLLDTEGLGDVEKGDPKNDL 111

  Fly   137 TVFALSTMLSSVQIYNLSQNIQEDDLQHLQLFTEYGRLALADTGKKP------------FQRLQF 189
            .:||||.:|||..|||....|....|:.|...||...|..|.:...|            |....:
Mouse   112 WIFALSVLLSSTFIYNSMITINHQALEQLHYVTELTELIRAKSSPNPAGIKNSTEFVSFFPDFVW 176

  Fly   190 LVRDWSFPYEAEYGALGGDKILKRRLEVSDKQHPELQ---SLRRHISSCFTEVACFLMPHP---- 247
            :|||:....:.....:..|..|:..|::.....|.:|   |.|..|...|....||:...|
Mouse   177 IVRDFMLELKLNGEDITSDDYLENALKLIPGDKPRMQASNSCRECIRLFFPNRKCFVFDRPTHDK 241

  Fly   248 ----GLNVATNPKFDGRLQDITPEFKSSLRSLVPMLLAPDNLVYKEI----SGQRVRARDLIQYF 304
                .|:..|..:.|.:.|::|..|.|.:            ..|.:|    .|.:|....|....
Mouse   242 ELLQKLDSITEDQLDPKFQEVTKAFVSYI------------FTYAKIKTLKEGIKVTGNKLGILV 294

  Fly   305 QSYMNIYKGNELPEPKSMLVATAEANHLTAVAAAKELYGQLMEEVCGGTRPYLSTAHLQ---TEH 366
            .:|::......:|.....:...|:..:..||..|.:.|.:.|.:     |..|.|..||   ..|
Mouse   295 TTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSEQMAQ-----RLRLPTETLQELLDVH 354

  Fly   367 LRVKDKALFQFAAKR-KMGGEEFTEKFRKQLEDDLEEVF--TNYQAHNE---------SKNIFKA 419
            ...:.:|:..|.... |...::|.:|. .:|..:.:|:|  .|.:|.|:         ||:..:.
Mouse   355 AACEKEAMAVFMEHSFKDENQQFLKKL-VELIGENKELFLSKNEEASNKYCQEELDRLSKDFMEN 418

  Fly   420 ARTPAVYFACAVIMYI 435
            ..|  .:..|...:|:
Mouse   419 IST--FFVPCGHKLYM 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atl	NP_001287506.1	GBP	14..289	CDD:280433	72/303 (24%)
atl	NP_001287506.1	MSC	<316..>471	CDD:286487	29/135 (21%)
Gbp10	NP_001034735.2	GBP	16..279	CDD:280433	72/305 (24%)
		GBP_C	281..575	CDD:202427	33/160 (21%)
		GBP_C	287..575	CDD:293879	31/154 (20%)
		coiled coil	544..555	CDD:293879
		coiled coil	564..575	CDD:293879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832126
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850