Protein Alignment atl and GBP2

DIOPT Version :10

• Sequence 1: NP_651274.1
• Gene: atl / 42934
• FlyBaseID: FBgn0039213
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_004111.2
• Gene: GBP2 / 2634
• HGNCID: 4183
• Length: 591
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 98/431 - (22%)
• Similarity: 167/431 - (38%)
• Gaps: 81/431 - (18%)

  Fly    38 VCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDATDWLGGESDPLEGFSWRGGSERDTTGILMWS 102
            |.||::.|.:|.|||:|:                 :.|.|:.:   |||.....:..|.||.||
Human    38 VVVVAIVGLYRTGKSYLM-----------------NKLAGKKN---GFSLGSTVKSHTKGIWMW- 81

  Fly   103 DIFLHDYPNGDKIAIILLDTQGAFD-SQSTVRDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQ 166
               ...:|...:..::||||:|..| .:....:.:.:|||:.:|||..:||....|.:..:..|.
Human    82 ---CVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLH 143

  Fly   167 LFTEY----------GRLALADTGK--KPFQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEV-- 217
            ..||.          |..::.|:..  ..|....:.:||::...|.:...:..|..|:..|::
Human   144 YVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRK 208

  Fly   218 -SDKQHPELQSLRRHISSCFTEVACFLMPHPGLNVATNPKFDGRL-----QDITPEFKSSLRSLV 276
             :||:.......|..|...|.:..||:...|     ...|:...|     :::.|:|...:....
Human   209 GTDKKSKSFNDPRLCIRKFFPKRKCFVFDWP-----APKKYLAHLEQLKEEELNPDFIEQVAEFC 268

  Fly   277 PMLLAPDNLVYKEISGQ-RVRARDLIQYFQSYMNIYKGNELPEPKSMLVATAEANHLTAVAAAKE 340
            ..:|:..|:  |.:||. .|....|.....:|:|.....:||..::.::|.|:..:..||..|..
Human   269 SYILSHSNV--KTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIA 331

  Fly   341 LYGQLMEEVCGGTRPYLSTAHLQTEHLRVKDKALFQFAAKRKMGGEEFTEKFRKQLEDDLEEVF- 404
            .|.|.|     |.:..|.|..||            :.....:....|..|.|.|....|::::|
Human   332 HYEQQM-----GQKVQLPTETLQ------------ELLDLHRDSEREAIEVFMKNSFKDVDQMFQ 379

  Fly   405 ----TNYQAHNESKNIFKAARTPAVYFACAVIMYILSGIFG 441
                ...:|..:.   |....:.|....|   |.:|..|||
Human   380 RKLGAQLEARRDD---FCKQNSKASSDCC---MALLQDIFG 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atl	NP_651274.1	GBP	14..289	CDD:460516	61/271 (23%)
GBP2	NP_004111.2	GTPase domain (Globular). /evidence=ECO:0000250|UniProtKB:P32455	1..309		69/301 (23%)
		GBP	18..280	CDD:460516	62/272 (23%)
		GBP_C	282..578	CDD:460721	35/156 (22%)