DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atl and unm_sa911

DIOPT Version :9

Sequence 1:	NP_001287506.1	Gene:	atl / 42934	FlyBaseID:	FBgn0039213	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_021323188.1	Gene:	unm_sa911 / 100334992	ZFINID:	ZDB-GENE-120727-3	Length:	629	Species:	Danio rerio

Alignment Length:	463	Identity:	111/463 - (23%)
Similarity:	174/463 - (37%)	Gaps:	115/463 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDATDWLGGESDPLEGFSWRGGSERDTTGILMWS 102
            |.||:|.|.:|.|||:||                 :.|.|:.   .||:.....|..|.||.||
Zfish    33 VVVVAVVGLYRTGKSYLL-----------------NRLAGKH---SGFALGSTVESKTKGIWMW- 76

  Fly   103 DIFLHDYPNGDKIAIILLDTQGAFD-SQSTVRDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQ 166
               ...:|...:..::||||:|..| .:...|..:.:|:|:.:|||..::|....|....::.||
Zfish    77 ---CVPHPTKAETTLLLLDTEGLGDVDKGDSRHDSNIFSLAVLLSSTLVFNSRGTIDNKAIEELQ 138

  Fly   167 LFTEYGRLALADTGKKP-------------FQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEV- 217
            ..||   |......|.|             |....:.|||:|...:.:......|:.|:..|::
Zfish   139 YVTE---LTECIKVKSPNEDVDNSTEFVKFFPSFIWAVRDFSLELKIDGEDATEDQYLEFALKLK 200

  Fly   218 --SDKQHPELQSLRRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDITPEFKSSLRSLVPMLL 280
              :.|:..|....|..|.:.|....||..|.|                .|.|..|:|..|.|..|
Zfish   201 HGTSKKVMEFNLPRECIKNFFPSRTCFTFPFP----------------TTLEKMSTLERLGPADL 249

  Fly   281 APDNLVYKEIS------------------GQRVRARDLIQYFQSYMNIYKGNELPEPKSMLVATA 327
            .|:   ::|:|                  |..|..|.|....:.|:|......:|..::.:||.|
Zfish   250 CPE---FQEVSKRFCTCVYEKSEVKRLKDGHTVTGRVLGHLAELYVNTISSGAVPCLENAVVALA 311

  Fly   328 EANHLTAVAAAKELYGQLMEEVCGGTRPY-LSTAHLQTEHLRVKDKALFQFAAKRKMGGEEFTE- 390
            :..:..|:..|.::|...|||   ..|.: |....:..||.|:...|...|.|      |.|.:
Zfish   312 QIENQAALQEALQVYQVGMEE---KKRAFPLELEQVSAEHQRLSQSATQTFMA------ESFRDT 367

  Fly   391 --KFRKQLEDDLEEVFTNYQAHNESKNIFKAARTPAVYFACAVIMYILS---------GIFGLVG 444
              |..|.||:::.::|......|:..::.|          |..::..||         |.:...|
Zfish   368 DGKHLKALEEEINKLFDACLRENDQASVKK----------CENLLLSLSATMTEKHKQGFYAKPG 422

  Fly   445 LYTFANFC 452
            .|..  ||
Zfish   423 GYDV--FC 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atl	NP_001287506.1	GBP	14..289	CDD:280433	68/267 (25%)
atl	NP_001287506.1	MSC	<316..>471	CDD:286487	35/150 (23%)
unm_sa911	XP_021323188.1	P-loop_NTPase	40..273	CDD:328724	66/278 (24%)
		GBP_C	281..571	CDD:293879	39/169 (23%)
		coiled coil	540..551	CDD:293879
		coiled coil	560..571	CDD:293879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920