Protein Alignment Syx18 and Stx18

DIOPT Version :9

• Sequence 1: NP_524485.1
• Gene: Syx18 / 42933
• FlyBaseID: FBgn0039212
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_081235.2
• Gene: Stx18 / 71116
• MGIID: 1918366
• Length: 334
• Species: Mus musculus
• Alignment Length: 400
• Identity: 130/400 - (32%)
• Similarity: 196/400 - (49%)
• Gaps: 77/400 - (19%)

  Fly     1 MDITQSFKASVMTVRLQRKA---ELAGKAKPATVPTKTGPIGPKDDFAKQAKEVCNKITSLRNVL 62
            :|||..|:|||.||:.:.||   .:.|.|..:..........||.||:.:|:||.:.|..||:.|
Mouse     3 VDITLLFRASVKTVKTRNKALGVAVGGGADGSRDELFRRSPRPKGDFSSRAREVISHIGKLRDFL 67

  Fly    63 IENRTAYMRIGQH-LKSAAHMTDAQRDLIDRESEKFVTFYTQHLAKMRSDWKSAKRKPQERQHID 126
            :|:|..|:....| :.....|||.:||.||::::.|:...::.:.::|::........|.::|..
Mouse    68 LEHRKEYINAYSHTMSDYGRMTDTERDQIDQDAQIFIRTCSEAIHQLRTEAHKEIHSQQVKEHRT 132

  Fly   127 AVLDLLVSYLHSVEQIYLDQKKYRVQHELETYRLLKLAAD---KKKIPVRPAGSNSGKLGRRQVS 188
            ||||.:..||..|.::|.:|:..||:..::..||.||..:   |:|
Mouse   133 AVLDFVDDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPHTKRK------------------- 178

  Fly   189 NDDSEATKSSSQANGNHDESADNDWNNDAWGDWDEDEEGDEVDDHDGEKGKEANQANQHKPRTRK 253
              ||.:.|:...|:                    :|.|           ||.|.:....||....
Mouse   179 --DSTSEKAPQNAS--------------------QDSE-----------GKPAAEELPEKPLAES 210

  Fly   254 RSKANRSDLNNSSSKMALDEELQQQQEADDDDPLSAEDVQLFEAENVHIYNFLQGVSEEVEQIEK 318
            :                  .||....:...:|.||.|::|:||.||..:...:..:.:||.|||.
Mouse   211 Q------------------PELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEG 257

  Fly   319 NVVDIAQLQDIFTEKVAMQQHNIDRIVSAVVGTTENVKDANEQIRQATQRNAGLRVWSLFFLLVM 383
            .||:|::||:||||||..|:..||.|...|||.|||:|:.||.||:|.:.|||.|||.||||::.
Mouse   258 KVVEISRLQEIFTEKVLQQETEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMC 322

  Fly   384 SFSLLFLDWY 393
            ||||||||||
Mouse   323 SFSLLFLDWY 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx18	NP_524485.1	Syntaxin-18_N	2..90	CDD:287468	33/91 (36%)
		SNARE_syntaxin18	306..364	CDD:277203	30/57 (53%)
Stx18	NP_081235.2	Syntaxin-18_N	4..96	CDD:287468	33/91 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..50		5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..225		18/128 (14%)
		SNARE_syntaxin18	245..303	CDD:277203	30/57 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848217
Domainoid	1	1.000	136	1.000	Domainoid score	I4925
eggNOG	1	0.900	-	-		E1_KOG3894
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9655
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3950
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004915
OrthoInspector	1	1.000	-	-		oto95258
orthoMCL	1	0.900	-	-		OOG6_103713
Panther	1	1.100	-	-	LDO	PTHR15959
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3600
SonicParanoid	1	1.000	-	-		X6026
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790