Protein Alignment Esyt2 and esyt1a

DIOPT Version :10

• Sequence 1: NP_001247287.1
• Gene: Esyt2 / 42929
• FlyBaseID: FBgn0266758
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_695611.3
• Gene: esyt1a / 567227
• ZFINID: ZDB-GENE-090311-55
• Length: 1079
• Species: Danio rerio
• Alignment Length: 1117
• Identity: 288/1117 - (25%)
• Similarity: 462/1117 - (41%)
• Gaps: 341/1117 - (30%)

  Fly    34 MNESPV-VTPTTPTGNGTP------PTQTTNGNSIVATKSVSDDNSIFSVFYTLGKKVAIVGSIY 91
            |.:||: |....|.....|      ||..:.|...|            ||.::.||.|.....:|
Zfish     1 MQKSPMSVDDAGPNAGAAPEAADAAPTTDSAGKHAV------------SVLWSFGKCVGAFLPVY 53

  Fly    92 LVGYMGWSVAWLIAPVILSV----ARDQLAKTSEKKRDIAKASALASEKDVILARI----DELPA 148
            |.||.|:|::.::..:::.:    :||     .:|.|..:....|.:|:||...|:    .:|||
Zfish    54 LAGYFGFSISVVLLGLLVYIGWKHSRD-----GKKARLQSAMYFLENEQDVTTTRVFRSKRDLPA 113

  Fly   149 WVYFPDVERCEWLNKILKQVWPNANHFARTLVKETIEPNVALALANYKMHGFRFDRIILGTIPPR 213
            ||.|||||:.||:||||:|.||....:...|:.|||.|::....|:  :....|.::.||....:
Zfish   114 WVNFPDVEKVEWINKILQQAWPFVGQYLEKLLVETIAPSIRATSAH--LQTLSFTKVDLGDRAMK 176

  Fly   214 IGGVKIYDKNVDRNEIIMDLDLFYASDCDINF----YLGGMKGGIKDFQIHGWVRVVMKPLIRSM 274
            :.|||.|.: .||.::|:||.:.||.|.:||.    |.  .|.|:|..|:||.:||:::|||..:
Zfish   177 VVGVKAYTE-FDRRQVILDLYISYAGDVEINVEVKKYF--CKAGVKGIQLHGKLRVILEPLIGDV 238

  Fly   275 PLVGGLQIFFLNNPNIDFNLVGVIDFMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVSAV 339
            ||||.:.:||:..|.:|.|..|:.:.:|:|||:.:...:|::.|.:.:||||:|.:.|...:...
Zfish   239 PLVGAITMFFIRRPKLDINWTGMTNLLDIPGLNAMSDTMIMDAIASFLVLPNRLTVPLVANLHVA 303

  Fly   340 ALKMPEPEGILRIHVVEAKDLMKKDISVLG--KGKSDPYAIINVGAQEFKTQIIDNNVNPKWDYW 402
            .|:.|.|.||:|||::||::|..||..:.|  .|||||||::.||.|.|.:..:|||:||:|...
Zfish   304 QLRSPLPRGIVRIHLLEAENLPAKDNYMKGVISGKSDPYAVLRVGTQIFTSHHVDNNLNPQWREM 368

  Fly   403 CEACIFTTIGHYIGFSLWDYDQTMPGVQSDDVLGRASIDIASVIKKGVVDSWLTLEDAKHGLLHV 467
            .|..:....|..:...::|.|.     ..||.|||..:|:..|.|..::|.|.||:||..|.:|:
Zfish   369 YEVIVHEVPGQELELEVFDKDP-----DQDDFLGRMKLDLGIVKKAVLLDEWYTLKDAASGQVHL 428

  Fly   468 RLQWYKLTADPNDLQQILLETQLLRVTSM-----SSAVLSVFIDSARHLKQARSSSKPDPYLVCS 527
            ||:|..|......|.::|...|.:.|.|.     |:|||:|::|.|:.|...:.:..|.|.:..|
Zfish   429 RLEWLSLLPSAERLSEVLERNQNITVPSKTADPPSAAVLTVYLDRAQDLPFKKGNKDPSPMVQIS 493

  Fly   528 VNKQKQQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGNDIGQYTYTLSTLLKQFNME 592
            |....:::..:...::|.||..|||.:.:|..:.::|::.|......:|.....:|.||....:
Zfish   494 VQDTTKESRTVYGTNNPAWEDAFTFFIQDPRKQDIDIQVKDDDRALTLGSLYIPMSRLLSSPEL- 557

  Fly   593 VIQQPFQLQKSGPESKLYMSLSLRIL--------------KPGE--------------------- 622
            .:.|.|||:||||.|::|::..||:|              .|||
Zfish   558 TMDQWFQLEKSGPASRIYITAMLRVLWLNEDAILTSPVSPIPGEGYGETEVSSGATKVTATPKRP 622

  Fly   623 ----------------------------------------------------------------- 622
                                                                             
Zfish   623 EHTSPDSNFASEGVLRIHLVEAQSLVAKDNLMGGMMKGKSDPYVKIRVGGLAFKSQVIKENLNPV 687

  Fly   623 ---------------------IDKDSD-------------------------------------- 628
                                 .|||.|
Zfish   688 WNELYEVILTQLPGQEVEFDLFDKDIDQDDFLGRVKVSLRDLISAQFTDQWYTLNDVKTGRIHLV 752

  Fly   629 -----------ALEQV----------------AAL---------------------------TRS 639
                       .|||:                |||                           .::
Zfish   753 LEWVPKISDPIRLEQILQYNYRQSYLNKIVPSAALLFVYIERAHGLPLKKSGKEPKAGAEVSLKN 817

  Fly   640 SSVKTPDVAAVSPPAFKES----------------------QA-SSKRLSAESPISEEDPV---- 677
            .|.:|..|...:.|.:.|:                      || .|..|.....:.|:|..
Zfish   818 VSYRTKVVNRSTSPQWDEALHFLIHNPTEDTLIVKVSHSWGQALGSLVLPVRELLEEKDLTIDRW 882

  Fly   678 ---------------AATKISPAMSASTSSEKPISEL---------ATSVLTHR-FP-----DST 712
                           |..|:..:..|..|.|:..|.:         |.|.|.|| .|     |::
Zfish   883 FSLNGAMPESQILLRAELKLLDSKLAQCSDEEDASHVIPSAEPTVAANSELRHRNVPVQGGEDAS 947

  Fly   713 SSPGEHGLGRMQLSIRYSAQRQKLDVTIHKIQKIP--LRDPSNIPDPYVKLYLLPGRTKESKRKT 775
            |:    |..:::|||.||::..:|.:.:|..:.:|  .::|   ||.|:...|||.:.:.:|:||
Zfish   948 ST----GKAQIKLSISYSSEEHRLIIKVHACRNLPSSSKEP---PDSYISFILLPDKNRNTKKKT 1005

  Fly   776 SVIKDNCNPVYDASFEYLISIAELRQTELEVTVCTQKGFLSGGSPIIGMLKI---PLDDAEITTQ 837
            ||.|.:..|.::..||:.:|:.|.:|..|||:|.....|:|....::|.|:|   |||     .:
Zfish  1006 SVKKKSLKPEFNEIFEFDMSLEEAKQKHLEVSVKNSVSFMSREKELLGKLQIDFSPLD-----LK 1065

  Fly   838 TGLNSWFDLQPE 849
            ||::.|:||..|
Zfish  1066 TGVSQWYDLSHE 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esyt2	NP_001247287.1	SMP_ESyt	156..332	CDD:439226	66/179 (37%)
		C2A_Synaptotagmin-like	348..471	CDD:175990	50/124 (40%)
		C2B_Synaptotagmin-like	500..605	CDD:176015	29/104 (28%)
		C2C_KIAA1228	719..847	CDD:175996	44/132 (33%)
esyt1a	XP_695611.3	SMP_ESyt1	121..296	CDD:439235	66/179 (37%)
		C2A_C2C_Synaptotagmin_like	312..432	CDD:176037	50/124 (40%)
		C2B_Synaptotagmin-like	466..570	CDD:176015	29/104 (28%)
		C2A_C2C_Synaptotagmin_like	635..755	CDD:176037	4/119 (3%)
		C2B_Synaptotagmin-like	787..890	CDD:176015	12/102 (12%)
		C2C_KIAA1228	950..1075	CDD:175996	44/132 (33%)