Protein Alignment Esyt2 and LOC100493597

DIOPT Version :10

• Sequence 1: NP_001247287.1
• Gene: Esyt2 / 42929
• FlyBaseID: FBgn0266758
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_031757229.1
• Gene: LOC100493597 / 100493597
• XenbaseID: XB-GENE-29081815
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 171/596 - (28%)
• Similarity: 296/596 - (49%)
• Gaps: 36/596 - (6%)

  Fly    82 KKVAIVGSIYLVGYMGWSVAWLIAPVILSVARDQLAKTSEKKRDIAKASALASEKDVILARIDEL 146
            |.|.|:...|.:|.:.:.:.::|  :||.|.:..:...|.::....|...:..||       .:.
 Frog    18 KYVLILVLSYFLGCLQFKIGYVI--LILLVLKCYMLWRSRRRPTEKKTEEIPKEK-------KKA 73

  Fly   147 PAWVYFPDVERCEWLNKILKQVWPNANHFARTLVKETIEPNVALALANYKMHGFRFDRIILGTIP 211
            |..|.....||.:.||.|.:.:||....:..|::::.|:|.:. :.:.| :...||..|..|..|
 Frog    74 PGRVPGEHFERSKSLNAIFENIWPYLTEYLETMLRQKIQPKIR-SSSKY-LASLRFINIDFGDKP 136

  Fly   212 PRIGGVKIYDKNVDRNEIIMDLDLFYASD--CDINFYLGGMKGGIKDFQIHGWVRVVMKPLIRSM 274
            |.:..::.:. :.:|.:||:||::.|.::  .||.|.......|:|..::.|.:|:::.||:...
 Frog   137 PEVTALRAHG-DPERKQIILDLEISYDTEVKIDIGFNEKTPIAGVKSIKLEGTLRIILAPLMEDA 200

  Fly   275 PLVGGLQIFFLNNPNIDFNLVGVIDFMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVSAV 339
            ||.|.:..:|.:.|.:|...:|:...:::|||..:..:.||.:|...||.|......:..:....
 Frog   201 PLFGAITFYFPHRPVLDLRWIGLTHLLNIPGLHTMSDKKIVNKIAKFMVAPQHFSQRIKAKFDLN 265

  Fly   340 ALKMPEPEGILRIHVVEAKDLMKKDISVLGKGKSDPYAIINVGAQEFKTQIIDNNVNPKWDYWCE 404
            .|...||..:|||||:|||:|..||:|     .||||.:|:.|....:|::|..|:||:|:...|
 Frog   266 ELHFKEPRIVLRIHVIEAKNLRAKDLS-----SSDPYVVIHGGGTTVQTKVIQKNLNPQWNETFE 325

  Fly   405 ACIFTTIGHYIGFSLWDYDQTMPGVQSDDVLGRASIDIASVIKKGVVDSWLTLEDAKHGLLHVRL 469
            .......|..:.|:|::.|:.:   ..|..||...|.||.|.::..:|.|:.||:|:.|.||::|
 Frog   326 ILYTDLPGQEVEFNLFNKDKEL---AKDQPLGSCKIRIADVPERMYLDKWIQLENAESGQLHIKL 387

  Fly   470 QWYKLTADPNDLQQILLE---TQLLRVTSMSSAVLSVFIDSARHLKQAR-SSSKPDPYLVCSVNK 530
            :..:|.:||..|:::|.|   ||..|.|.||||||..||:.||.|...: ...|.:|..|..|..
 Frog   388 ERLQLLSDPTKLEEVLKENEQTQTERRTQMSSAVLYTFIEKARGLPVVQVQKGKLNPLAVVQVAV 452

  Fly   531 QK--QQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGNDIGQYTYTLSTLLKQFNMEV 593
            |.  |:|...:::....|::.|.||:.||..|.|.:.::|::. ..:|.....||.|:...:| .
 Frog   453 QDSVQETGSKVKNGEVEWKRRFQFLLRNPLTEELKLMLHDERQ-KPLGCVAVPLSQLVDAADM-T 515

  Fly   594 IQQPFQLQKSGPESKLYMSLSLRILKPGEIDKDSDALEQV-AALTRSSSVKTPDVAAVSPPAFKE 657
            |:....|:.:.....:.:.|.||||.|.......:  ||: ..:||.........|.:|.   ::
 Frog   516 IEDWLPLESTEENRDIRVKLQLRILAPHPYSVKEE--EQIPEEITRVPLFHGETKAQISK---RK 575

  Fly   658 SQASSKRLSAE 668
            |.|..::|.|:
 Frog   576 SWAKVRKLFAK 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esyt2	NP_001247287.1	SMP_ESyt	156..332	CDD:439226	48/177 (27%)
		C2A_Synaptotagmin-like	348..471	CDD:175990	45/122 (37%)
		C2B_Synaptotagmin-like	500..605	CDD:176015	30/107 (28%)
		C2C_KIAA1228	719..847	CDD:175996
LOC100493597	XP_031757229.1	SMP_ESyt	83..255	CDD:439226	48/174 (28%)
		C2	275..388	CDD:472691	44/120 (37%)
		C2	421..526	CDD:472691	30/106 (28%)